A far-red emitting probe for unambiguous detection of mobile zinc in acidic vesicles and deep tissue
Imaging mobile zinc in acidic environments remains challenging because most small-molecule optical probes display pH-dependent fluorescence. Here we report a reaction-based sensor that detects mobile zinc unambiguously at low pH. The sensor responds reversibly and with a large dynamic range to exoge...
Main Authors: | Khan, Mustafa, Georgiou, John, Luyben, Thomas T., Roder, John C., Okamoto, Kenichi, Rivera Fuentes, Pablo Marcelo, Wrobel, Alexandra T., Zastrow, Melissa L., Lippard, Stephen J. |
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Other Authors: | Massachusetts Institute of Technology. Department of Chemistry |
Format: | Article |
Language: | en_US |
Published: |
Royal Society of Chemistry, The
2017
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Online Access: | http://hdl.handle.net/1721.1/110418 https://orcid.org/0000-0002-5910-6948 https://orcid.org/0000-0002-2693-4982 |
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