Viral genome imaging of hepatitis C virus to probe heterogeneous viral infection and responses to antiviral therapies

Viral genome imaging of hepatitis C virus to probe heterogeneous viral infection and responses to antiviral therapies

Hepatitis C virus (HCV) is a positive single-stranded RNA virus of enormous global health importance, with direct-acting antiviral therapies replacing an immunostimulatory interferon-based regimen. The dynamics of HCV positive and negative-strand viral RNAs (vRNAs) under antiviral perturbations have...

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Bibliographic Details
Main Authors: Luna, Joseph M., Hoffmann, Hans.-Heinrich, Espiritu, Christine, Sheahan, Timothy P., Rice, Charles M., Ramanan, Vyas, Trehan, Kartik, Ong, Mei Lyn, Chandrasekar, Hamsika, Christine, Kathleen, van Oudenaarden, Alexander, Bhatia, Sangeeta N, Schwartz, Robert E.
Other Authors: Massachusetts Institute of Technology. Institute for Medical Engineering & Science
Format: Article
Language:en_US
Published: Elsevier 2017
Online Access:http://hdl.handle.net/1721.1/110773
https://orcid.org/0000-0001-6214-4788
https://orcid.org/0000-0002-1293-2097

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