Cubic meter volume optical coherence tomography

Optical coherence tomography (OCT) is a powerful three-dimensional (3D) imaging modality with micrometer-scale axial resolution and up to multi-GigaVoxel/s imaging speed. However, the imaging range of high-speed OCT has been limited. Here, we report 3D OCT over cubic meter volumes using a long coh...

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Main Authors: Chen, Long, Doerr, Chris, Nielson, Torben, Jayaraman, Vijaysekhar, Cable, Alex E., Wang, Zhao, Potsaid, Benjamin M., Lee, Hsiang-Chieh, Swanson, Eric A, Fujimoto, James G
Other Authors: Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science
Format: Article
Language:en_US
Published: Optical Society of America 2017
Online Access:http://hdl.handle.net/1721.1/110905
https://orcid.org/0000-0002-9724-5164
https://orcid.org/0000-0002-2976-6195
https://orcid.org/0000-0002-0828-4357
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author Chen, Long
Doerr, Chris
Nielson, Torben
Jayaraman, Vijaysekhar
Cable, Alex E.
Wang, Zhao
Potsaid, Benjamin M.
Lee, Hsiang-Chieh
Swanson, Eric A
Fujimoto, James G
author2 Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science
author_facet Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science
Chen, Long
Doerr, Chris
Nielson, Torben
Jayaraman, Vijaysekhar
Cable, Alex E.
Wang, Zhao
Potsaid, Benjamin M.
Lee, Hsiang-Chieh
Swanson, Eric A
Fujimoto, James G
author_sort Chen, Long
collection MIT
description Optical coherence tomography (OCT) is a powerful three-dimensional (3D) imaging modality with micrometer-scale axial resolution and up to multi-GigaVoxel/s imaging speed. However, the imaging range of high-speed OCT has been limited. Here, we report 3D OCT over cubic meter volumes using a long coherence length, 1310 nm vertical-cavity surface-emitting laser and silicon photonic integrated circuit dual-quadrature receiver technology combined with enhanced signal processing. We achieved 15 μm depth resolution for tomographic imaging at a 100 kHz axial scan rate over a 1.5 m range. We show 3D macroscopic imaging examples of a human mannequin, bicycle, machine shop gauge blocks, and a human skull/brain model. High-bandwidth, meter-range OCT demonstrates new capabilities that promise to enable a wide range of biomedical, scientific, industrial, and research applications.
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spelling mit-1721.1/1109052022-09-28T18:02:35Z Cubic meter volume optical coherence tomography Chen, Long Doerr, Chris Nielson, Torben Jayaraman, Vijaysekhar Cable, Alex E. Wang, Zhao Potsaid, Benjamin M. Lee, Hsiang-Chieh Swanson, Eric A Fujimoto, James G Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science Massachusetts Institute of Technology. Research Laboratory of Electronics Wang, Zhao Potsaid, Benjamin M. Lee, Hsiang-Chieh Swanson, Eric A Fujimoto, James G Optical coherence tomography (OCT) is a powerful three-dimensional (3D) imaging modality with micrometer-scale axial resolution and up to multi-GigaVoxel/s imaging speed. However, the imaging range of high-speed OCT has been limited. Here, we report 3D OCT over cubic meter volumes using a long coherence length, 1310 nm vertical-cavity surface-emitting laser and silicon photonic integrated circuit dual-quadrature receiver technology combined with enhanced signal processing. We achieved 15 μm depth resolution for tomographic imaging at a 100 kHz axial scan rate over a 1.5 m range. We show 3D macroscopic imaging examples of a human mannequin, bicycle, machine shop gauge blocks, and a human skull/brain model. High-bandwidth, meter-range OCT demonstrates new capabilities that promise to enable a wide range of biomedical, scientific, industrial, and research applications. National Institutes of Health (U.S.) (R01- EY011289-30) National Institutes of Health (U.S.) (R01-CA075289-19) National Institutes of Health (U.S.) (RO1-CA178636-02) National Institutes of Health (U.S.) (R44- EY022864-03) United States. Air Force Office of Scientific Research (FA9550-12-1-0551) United States. Air Force Office of Scientific Research (FA9550-15-1-0473) 2017-08-02T14:42:47Z 2017-08-02T14:42:47Z 2016-12 2016-10 Article http://purl.org/eprint/type/JournalArticle 2334-2536 http://hdl.handle.net/1721.1/110905 Wang, Zhao; Potsaid, Benjamin; Chen, Long et al. “Cubic Meter Volume Optical Coherence Tomography.” Optica 3, 12 (December 2016): 1496-1503 © 2016 Optical Society of America https://orcid.org/0000-0002-9724-5164 https://orcid.org/0000-0002-2976-6195 https://orcid.org/0000-0002-0828-4357 en_US http://dx.doi.org/10.1364/OPTICA.3.001496 Optica Creative Commons Attribution-Noncommercial-Share Alike http://creativecommons.org/licenses/by-nc-sa/4.0/ application/pdf Optical Society of America PMC
spellingShingle Chen, Long
Doerr, Chris
Nielson, Torben
Jayaraman, Vijaysekhar
Cable, Alex E.
Wang, Zhao
Potsaid, Benjamin M.
Lee, Hsiang-Chieh
Swanson, Eric A
Fujimoto, James G
Cubic meter volume optical coherence tomography
title Cubic meter volume optical coherence tomography
title_full Cubic meter volume optical coherence tomography
title_fullStr Cubic meter volume optical coherence tomography
title_full_unstemmed Cubic meter volume optical coherence tomography
title_short Cubic meter volume optical coherence tomography
title_sort cubic meter volume optical coherence tomography
url http://hdl.handle.net/1721.1/110905
https://orcid.org/0000-0002-9724-5164
https://orcid.org/0000-0002-2976-6195
https://orcid.org/0000-0002-0828-4357
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