Keypoint Transfer Segmentation

We present an image segmentation method that transfers label maps of entire organs from the training images to the novel image to be segmented. The transfer is based on sparse correspondences between keypoints that represent automatically identified distinctive image locations. Our segmentation algo...

Full description

Bibliographic Details
Main Authors: Toews, M., Wachinger, Christian, Langs, Georg, Wells, William M, Golland, Polina
Other Authors: Massachusetts Institute of Technology. Computer Science and Artificial Intelligence Laboratory
Format: Article
Language:en_US
Published: 2017
Online Access:http://hdl.handle.net/1721.1/110912
https://orcid.org/0000-0002-3652-1874
https://orcid.org/0000-0003-2516-731X
_version_ 1826192577712357376
author Toews, M.
Wachinger, Christian
Langs, Georg
Wells, William M
Golland, Polina
author2 Massachusetts Institute of Technology. Computer Science and Artificial Intelligence Laboratory
author_facet Massachusetts Institute of Technology. Computer Science and Artificial Intelligence Laboratory
Toews, M.
Wachinger, Christian
Langs, Georg
Wells, William M
Golland, Polina
author_sort Toews, M.
collection MIT
description We present an image segmentation method that transfers label maps of entire organs from the training images to the novel image to be segmented. The transfer is based on sparse correspondences between keypoints that represent automatically identified distinctive image locations. Our segmentation algorithm consists of three steps: (i) keypoint matching, (ii) voting-based keypoint labeling, and (iii) keypoint-based probabilistic transfer of organ label maps. We introduce generative models for the inference of keypoint labels and for image segmentation, where keypoint matches are treated as a latent random variable and are marginalized out as part of the algorithm. We report segmentation results for abdominal organs in whole-body CT and in contrast-enhanced CT images. The accuracy of our method compares favorably to common multi-atlas segmentation while offering a speed-up of about three orders of magnitude. Furthermore, keypoint transfer requires no training phase or registration to an atlas. The algorithm’s robustness enables the segmentation of scans with highly variable field-of-view.
first_indexed 2024-09-23T09:21:09Z
format Article
id mit-1721.1/110912
institution Massachusetts Institute of Technology
language en_US
last_indexed 2024-09-23T09:21:09Z
publishDate 2017
record_format dspace
spelling mit-1721.1/1109122022-09-26T11:19:10Z Keypoint Transfer Segmentation Toews, M. Wachinger, Christian Langs, Georg Wells, William M Golland, Polina Massachusetts Institute of Technology. Computer Science and Artificial Intelligence Laboratory Wachinger, Christian Langs, Georg Wells, William M Golland, Polina We present an image segmentation method that transfers label maps of entire organs from the training images to the novel image to be segmented. The transfer is based on sparse correspondences between keypoints that represent automatically identified distinctive image locations. Our segmentation algorithm consists of three steps: (i) keypoint matching, (ii) voting-based keypoint labeling, and (iii) keypoint-based probabilistic transfer of organ label maps. We introduce generative models for the inference of keypoint labels and for image segmentation, where keypoint matches are treated as a latent random variable and are marginalized out as part of the algorithm. We report segmentation results for abdominal organs in whole-body CT and in contrast-enhanced CT images. The accuracy of our method compares favorably to common multi-atlas segmentation while offering a speed-up of about three orders of magnitude. Furthermore, keypoint transfer requires no training phase or registration to an atlas. The algorithm’s robustness enables the segmentation of scans with highly variable field-of-view. National Alliance for Medical Image Computing (U.S.) (U54-EB005149) National Center for Image Guided Therapy (P41-EB015898) 2017-08-02T16:05:49Z 2017-08-02T16:05:49Z 2015-06 2017-08-02 2015-06 Article http://purl.org/eprint/type/ConferencePaper 978-3-319-19991-7 978-3-319-19992-4 0302-9743 1611-3349 http://hdl.handle.net/1721.1/110912 Wachinger, C.; Toews, M.; Langs, G.; Wells, W. et al. “Keypoint Transfer Segmentation.” Information Processing in Medical Imaging (2015): 233–245 © Springer International Publishing Switzerland 2015 https://orcid.org/0000-0002-3652-1874 https://orcid.org/0000-0003-2516-731X en_US http://dx.doi.org/10.1007/978-3-319-19992-4_18 Information Processing in Medical Imaging Creative Commons Attribution-Noncommercial-Share Alike http://creativecommons.org/licenses/by-nc-sa/4.0/ application/pdf PMC
spellingShingle Toews, M.
Wachinger, Christian
Langs, Georg
Wells, William M
Golland, Polina
Keypoint Transfer Segmentation
title Keypoint Transfer Segmentation
title_full Keypoint Transfer Segmentation
title_fullStr Keypoint Transfer Segmentation
title_full_unstemmed Keypoint Transfer Segmentation
title_short Keypoint Transfer Segmentation
title_sort keypoint transfer segmentation
url http://hdl.handle.net/1721.1/110912
https://orcid.org/0000-0002-3652-1874
https://orcid.org/0000-0003-2516-731X
work_keys_str_mv AT toewsm keypointtransfersegmentation
AT wachingerchristian keypointtransfersegmentation
AT langsgeorg keypointtransfersegmentation
AT wellswilliamm keypointtransfersegmentation
AT gollandpolina keypointtransfersegmentation