Integrated Gut and Liver Microphysiological Systems for Quantitative In Vitro Pharmacokinetic Studies
Investigation of the pharmacokinetics (PK) of a compound is of significant importance during the early stages of drug development, and therefore several in vitro systems are routinely employed for this purpose. However, the need for more physiologically realistic in vitro models has recently fueled...
Main Authors: | Stokes, Cynthia L, Tsamandouras, Nikolaos, Chen, Wen Li, Edington, Collin D, Griffith, Linda G, Cirit, Murat |
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Other Authors: | Massachusetts Institute of Technology. Department of Biological Engineering |
Format: | Article |
Language: | English |
Published: |
American Association of Pharmaceutical Scientists
2017
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Online Access: | http://hdl.handle.net/1721.1/111057 https://orcid.org/0000-0003-1137-0413 https://orcid.org/0000-0002-5248-871X https://orcid.org/0000-0002-1801-5548 |
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