Scene-selective coding by single neurons in the human parahippocampal cortex
Imaging, electrophysiological, and lesion studies have shown a relationship between the parahippocampal cortex (PHC) and the processing of spatial scenes. Our present knowledge of PHC, however, is restricted to the macroscopic properties and dynamics of bulk tissue; the behavior and selectivity of s...
| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | en_US |
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National Academy of Sciences (U.S.)
2017
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| Online Access: | http://hdl.handle.net/1721.1/111214 https://orcid.org/0000-0002-9088-2443 |
| _version_ | 1826199911499038720 |
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| author | Mormann, Florian Cerf, Moran Ison, Matias J. Kraskov, Alexander Tran, Michelle Knieling, Simeon Quian Quiroga, Rodrigo Koch, Christof Fried, Itzhak Kornblith, Simon John |
| author2 | Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences |
| author_facet | Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences Mormann, Florian Cerf, Moran Ison, Matias J. Kraskov, Alexander Tran, Michelle Knieling, Simeon Quian Quiroga, Rodrigo Koch, Christof Fried, Itzhak Kornblith, Simon John |
| author_sort | Mormann, Florian |
| collection | MIT |
| description | Imaging, electrophysiological, and lesion studies have shown a relationship between the parahippocampal cortex (PHC) and the processing of spatial scenes. Our present knowledge of PHC, however, is restricted to the macroscopic properties and dynamics of bulk tissue; the behavior and selectivity of single parahippocampal neurons remains largely unknown. In this study, we analyzed responses from 630 parahippocampal neurons in 24 neurosurgical patients during visual stimulus presentation. We found a spatially clustered subpopulation of scene-selective units with an associated event-related field potential. These units form a population code that is more distributed for scenes than for other stimulus categories, and less sparse than elsewhere in the medial temporal lobe. Our electrophysiological findings provide insight into how individual units give rise to the population response observed with functional imaging in the parahippocampal place area. |
| first_indexed | 2024-09-23T11:27:46Z |
| format | Article |
| id | mit-1721.1/111214 |
| institution | Massachusetts Institute of Technology |
| language | en_US |
| last_indexed | 2024-09-23T11:27:46Z |
| publishDate | 2017 |
| publisher | National Academy of Sciences (U.S.) |
| record_format | dspace |
| spelling | mit-1721.1/1112142022-09-27T19:43:13Z Scene-selective coding by single neurons in the human parahippocampal cortex Mormann, Florian Cerf, Moran Ison, Matias J. Kraskov, Alexander Tran, Michelle Knieling, Simeon Quian Quiroga, Rodrigo Koch, Christof Fried, Itzhak Kornblith, Simon John Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences Kornblith, Simon John Imaging, electrophysiological, and lesion studies have shown a relationship between the parahippocampal cortex (PHC) and the processing of spatial scenes. Our present knowledge of PHC, however, is restricted to the macroscopic properties and dynamics of bulk tissue; the behavior and selectivity of single parahippocampal neurons remains largely unknown. In this study, we analyzed responses from 630 parahippocampal neurons in 24 neurosurgical patients during visual stimulus presentation. We found a spatially clustered subpopulation of scene-selective units with an associated event-related field potential. These units form a population code that is more distributed for scenes than for other stimulus categories, and less sparse than elsewhere in the medial temporal lobe. Our electrophysiological findings provide insight into how individual units give rise to the population response observed with functional imaging in the parahippocampal place area. 2017-09-14T18:51:53Z 2017-09-14T18:51:53Z 2017-01 2016-05 Article http://purl.org/eprint/type/JournalArticle 0027-8424 1091-6490 http://hdl.handle.net/1721.1/111214 Mormann, Florian et al. “Scene-Selective Coding by Single Neurons in the Human Parahippocampal Cortex.” Proceedings of the National Academy of Sciences 114, 5 (January 2017): 1153–1158 © National Academy of Sciences https://orcid.org/0000-0002-9088-2443 en_US http://dx.doi.org/10.1073/pnas.1608159113 Proceedings of the National Academy of Sciences Article is made available in accordance with the publisher's policy and may be subject to US copyright law. Please refer to the publisher's site for terms of use. application/pdf National Academy of Sciences (U.S.) PNAS |
| spellingShingle | Mormann, Florian Cerf, Moran Ison, Matias J. Kraskov, Alexander Tran, Michelle Knieling, Simeon Quian Quiroga, Rodrigo Koch, Christof Fried, Itzhak Kornblith, Simon John Scene-selective coding by single neurons in the human parahippocampal cortex |
| title | Scene-selective coding by single neurons in the human parahippocampal cortex |
| title_full | Scene-selective coding by single neurons in the human parahippocampal cortex |
| title_fullStr | Scene-selective coding by single neurons in the human parahippocampal cortex |
| title_full_unstemmed | Scene-selective coding by single neurons in the human parahippocampal cortex |
| title_short | Scene-selective coding by single neurons in the human parahippocampal cortex |
| title_sort | scene selective coding by single neurons in the human parahippocampal cortex |
| url | http://hdl.handle.net/1721.1/111214 https://orcid.org/0000-0002-9088-2443 |
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