Development and Applications of CRISPR-Cas9 for Genome Engineering
Recent advances in genome engineering technologies based on the CRISPR-associated RNA-guided endonuclease Cas9 are enabling the systematic interrogation of mammalian genome function. Analogous to the search function in modern word processors, Cas9 can be guided to specific locations within complex g...
Main Authors: | Hsu, Patrick, Lander, Eric Steven, Zhang, Feng |
---|---|
Other Authors: | Massachusetts Institute of Technology. Department of Biological Engineering |
Format: | Article |
Language: | en_US |
Published: |
Elsevier
2017
|
Online Access: | http://hdl.handle.net/1721.1/111575 https://orcid.org/0000-0003-2782-2509 |
Similar Items
-
Genome engineering using the CRISPR-Cas9 system
by: Ran, F. Ann, et al.
Published: (2016) -
Genome-scale transcriptional activation by an engineered CRISPR-Cas9 complex
by: Konermann, Silvana, et al.
Published: (2016) -
CRISPR/Cas9 Delivery System Engineering for Genome Editing in Therapeutic Applications
by: Hao Cheng, et al.
Published: (2021-10-01) -
Genetic Screens in Human Cells Using the CRISPR-Cas9 System
by: Wang, Tim, et al.
Published: (2015) -
Multiplex Genome Engineering Using CRISPR/Cas Systems
by: Cong, Le, et al.
Published: (2016)