Functional differences between PD-1⁺ and PD-1⁻CD4⁺ effector T cells in healthy donors and patients with glioblastoma multiforme
mmune checkpoint inhibitors targeting programmed cell death protein 1 (PD-1) have been highly successful in the treatment of cancer. While PD-1 expression has been widely investigated, its role in CD4⁺ effector T cells in the setting of health and cancer remains unclear, particularly in the setting...
Main Authors: | Hernandez, Amanda L., Lowther, Daniel E., Lucca, Liliana E., Lerner, Benjamin A., Gunel, Murat, Raddassi, Khadir, Coric, Vlad, Hafler, David A., Thomas, Brittany A., Love, John C |
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Other Authors: | Massachusetts Institute of Technology. Department of Biological Engineering |
Format: | Article |
Language: | en_US |
Published: |
Public Library of Science
2017
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Online Access: | http://hdl.handle.net/1721.1/111673 https://orcid.org/0000-0002-5962-9570 https://orcid.org/0000-0003-0921-3144 |
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