Essays on learning and strategy in research and development

Thesis: Ph. D., Massachusetts Institute of Technology, Sloan School of Management, 2017.

Bibliographic Details
Main Author: Krieger, Joshua Lev
Other Authors: Pierre Azoulay.
Format: Thesis
Language:eng
Published: Massachusetts Institute of Technology 2017
Subjects:
Online Access:http://hdl.handle.net/1721.1/112028
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author Krieger, Joshua Lev
author2 Pierre Azoulay.
author_facet Pierre Azoulay.
Krieger, Joshua Lev
author_sort Krieger, Joshua Lev
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description Thesis: Ph. D., Massachusetts Institute of Technology, Sloan School of Management, 2017.
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spelling mit-1721.1/1120282019-04-12T22:46:06Z Essays on learning and strategy in research and development Krieger, Joshua Lev Pierre Azoulay. Sloan School of Management. Sloan School of Management. Sloan School of Management. Thesis: Ph. D., Massachusetts Institute of Technology, Sloan School of Management, 2017. Cataloged from PDF version of thesis. Includes bibliographical references. This dissertation investigates how research organizations learn from and adapt to new knowledge. In particular, I examine how news about scandals, stigmas and failures influences the direction of research and development efforts. These negative information shocks force research organizations to pause, interpret external signals, and apply any lessons to their own project portfolios. I investigate how these negative information events impact decisions in the settings of scientific publishing and drug development. In the first essay, I study the impact of scientific retractions on citation patterns and funding in the retracted paper's intellectual field. I investigate how the retraction disclosure and affected field's characteristics influence the extent of these spillover effects. The second essay evaluates how retraction scandals damage individual scientists' reputations. This study shows that the magnitude of the retraction penalty depends on a scientist's prominence and whether or not the retraction event involved "misconduct." In the third essay, I analyze how late-stage drug development failures alter competitor's project continuation decisions. I separate technological learning effects from market competition effects, and grade decision-making across firms. by Joshua Lev Krieger. 1. Introduction -- 2. Retractions (with Pierre Azoulay, Jeffrey Furman, and Fiona Murray) -- 3. The Career Effects of Scandal: Evidence from Scientific Retractions (with Pierre Azoulay and Alessandro Bonatti) -- 4. Trials and Terminations: Learning from Competitors' R&D Failures. Ph. D. 2017-10-30T15:28:20Z 2017-10-30T15:28:20Z 2017 2017 Thesis http://hdl.handle.net/1721.1/112028 1006379434 eng MIT theses are protected by copyright. They may be viewed, downloaded, or printed from this source but further reproduction or distribution in any format is prohibited without written permission. http://dspace.mit.edu/handle/1721.1/7582 216 pages application/pdf Massachusetts Institute of Technology
spellingShingle Sloan School of Management.
Krieger, Joshua Lev
Essays on learning and strategy in research and development
title Essays on learning and strategy in research and development
title_full Essays on learning and strategy in research and development
title_fullStr Essays on learning and strategy in research and development
title_full_unstemmed Essays on learning and strategy in research and development
title_short Essays on learning and strategy in research and development
title_sort essays on learning and strategy in research and development
topic Sloan School of Management.
url http://hdl.handle.net/1721.1/112028
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