The guanine-nucleotide exchange factor CalDAG GEFI fine-tunes functional properties of regulatory T cells

The guanine-nucleotide exchange factor CalDAG GEFI fine-tunes functional properties of regulatory T cells

Using quantitative phosphopeptide sequencing of unstimulated versus stimulated primary murine Foxp3(+) regulatory and Foxp3(-) conventional T cells (Tregs and Tconv, respectively), we detected a novel and differentially regulated tyrosine phosphorylation site within the C1 domain of the guanine-nucl...

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Bibliographic Details
Main Authors: Niemz, Jana, Kliche, Stefanie, Pils, Marina C., Morrison, Eliot, Manns, Annika, Freund, Christian, Galla, Melanie, Jänsch, Lothar, Huehn, Jochen, Crittenden, Jill R, Graybiel, Ann M
Other Authors: Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences
Format: Article
Published: Akademiai Kiado RT 2017
Online Access:http://hdl.handle.net/1721.1/112185
https://orcid.org/0000-0002-4326-7720

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