Foxp2 controls synaptic wiring of corticostriatal circuits and vocal communication by opposing Mef2c

Foxp2 controls synaptic wiring of corticostriatal circuits and vocal communication by opposing Mef2c

Cortico-basal ganglia circuits are critical for speech and language and are implicated in autism spectrum disorder, in which language function can be severely affected. We demonstrate that in the mouse striatum, the gene Foxp2 negatively interacts with the synapse suppressor gene Mef2c. We present c...

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Bibliographic Details
Main Authors: Chen, Yi-Chuan, Kuo, Hsiao-Ying, Bornschein, Ulrich, Takahashi, Hiroshi, Chen, Shih-Yun, Lu, Kuan-Ming, Yang, Hao-Yu, Chen, Gui-May, Lin, Jing-Ruei, Lee, Yi-Hsin, Chou, Yun-Chia, Cheng, Sin-Jhong, Chien, Cheng-Ting, Enard, Wolfgang, Hevers, Wulf, Pääbo, Svante, Graybiel, Ann M, Liu, Fu-Chin
Other Authors: McGovern Institute for Brain Research at MIT
Format: Article
Published: Springer Nature 2017
Online Access:http://hdl.handle.net/1721.1/112187
https://orcid.org/0000-0002-4326-7720

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