Dicer loss and recovery induce an oncogenic switch driven by transcriptional activation of the oncofetal Imp1–3 family
MicroRNAs(miRNAs) are post-transcriptional regulators of gene expressioncritical for organismal viability. Changes inmiRNAactivity arecommonin cancer, buthowthese changes relate to subsequent alterations in transcription and the process of tumorigenesis is not well understood. Here, we report a deep...
| Main Authors: | , , , , , , |
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| Format: | Article |
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Cold Spring Harbor Laboratory
2017
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| Online Access: | http://hdl.handle.net/1721.1/112212 https://orcid.org/0000-0001-8353-9316 https://orcid.org/0000-0002-2902-7288 https://orcid.org/0000-0001-5785-8911 https://orcid.org/0000-0003-1465-1691 |