Adult restoration of Shank3 expression rescues selective autistic-like phenotypes
Because autism spectrum disorders are neurodevelopmental disorders and patients typically display symptoms before the age of three, one of the key questions in autism research is whether the pathology is reversible in adults. Here we investigate the developmental requirement of Shank3 in mice, a pro...
Main Authors: | Mei, Yuan, Monteiro, Patricia, Zhou, Yang, Kim, Jinah, Gao, Xian, Fu, Zhanyan, Feng, Guoping |
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Other Authors: | Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences |
Format: | Article |
Published: |
Nature Publishing Group
2017
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Online Access: | http://hdl.handle.net/1721.1/112266 https://orcid.org/0000-0002-5596-1269 https://orcid.org/0000-0003-3288-4560 https://orcid.org/0000-0002-2196-8737 https://orcid.org/0000-0002-1069-235X https://orcid.org/0000-0001-9473-2402 https://orcid.org/0000-0002-8021-277X |
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