BLISS is a versatile and quantitative method for genome-wide profiling of DNA double-strand breaks

BLISS is a versatile and quantitative method for genome-wide profiling of DNA double-strand breaks

Precisely measuring the location and frequency of DNA double-strand breaks (DSBs) along the genome is instrumental to understanding genomic fragility, but current methods are limited in versatility, sensitivity or practicality. Here we present Breaks Labeling In Situ and Sequencing (BLISS), featurin...

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Bibliographic Details
Main Authors: Mirzazadeh, Reza, Garnerone, Silvano, Schneider, Martin W., Kallas, Tomasz, Custodio, Joaquin, Wernersson, Erik, Bienko, Magda, Crosetto, Nicola, Yan, Winston Xia, Scott, David Arthur, Li, Yinqing, Gao, Linyi, Federova, Yana, Zetsche, Bernd, Zhang, Feng
Other Authors: Harvard University--MIT Division of Health Sciences and Technology
Format: Article
Published: Nature Publishing Group 2017
Online Access:http://hdl.handle.net/1721.1/112285
https://orcid.org/0000-0002-3067-479X
https://orcid.org/0000-0002-2639-9879
https://orcid.org/0000-0002-3579-0327
https://orcid.org/0000-0003-2782-2509

Internet

http://hdl.handle.net/1721.1/112285
https://orcid.org/0000-0002-3067-479X
https://orcid.org/0000-0002-2639-9879
https://orcid.org/0000-0002-3579-0327
https://orcid.org/0000-0003-2782-2509

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