Genome editing abrogates angiogenesis in vivo

Angiogenesis, in which vascular endothelial growth factor receptor (VEGFR) 2 plays an essential role, is associated with a variety of human diseases including proliferative diabetic retinopathy and wet age-related macular degeneration. Here we report that a system of adeno-associated virus (AAV)-med...

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Bibliographic Details
Main Authors: Huang, Xionggao, Zhou, Guohong, Wu, Wenyi, Duan, Yajian, Ma, Gaoen, Song, Jingyuan, Xiao, Ru, Vandenberghe, Luk, Zhang, Feng, D’Amore, Patricia A., Lei, Hetian
Other Authors: Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences
Format: Article
Published: Nature Publishing Group 2017
Online Access:http://hdl.handle.net/1721.1/112302
https://orcid.org/0000-0003-2782-2509