Effects of cross-link and myosin motor concentrations on active muscle gel contraction time and extent
Thesis: S.B., Massachusetts Institute of Technology, Department of Mechanical Engineering, 2017.
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| Format: | Thesis |
| Language: | eng |
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Massachusetts Institute of Technology
2017
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| Online Access: | http://hdl.handle.net/1721.1/112565 |
| _version_ | 1826203654482296832 |
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| author | Babcock, Joseph M. (Joseph Michel) |
| author2 | Anette Hosoi. |
| author_facet | Anette Hosoi. Babcock, Joseph M. (Joseph Michel) |
| author_sort | Babcock, Joseph M. (Joseph Michel) |
| collection | MIT |
| description | Thesis: S.B., Massachusetts Institute of Technology, Department of Mechanical Engineering, 2017. |
| first_indexed | 2024-09-23T12:40:57Z |
| format | Thesis |
| id | mit-1721.1/112565 |
| institution | Massachusetts Institute of Technology |
| language | eng |
| last_indexed | 2024-09-23T12:40:57Z |
| publishDate | 2017 |
| publisher | Massachusetts Institute of Technology |
| record_format | dspace |
| spelling | mit-1721.1/1125652019-04-11T05:19:47Z Effects of cross-link and myosin motor concentrations on active muscle gel contraction time and extent Babcock, Joseph M. (Joseph Michel) Anette Hosoi. Massachusetts Institute of Technology. Department of Mechanical Engineering. Massachusetts Institute of Technology. Department of Mechanical Engineering. Mechanical Engineering. Thesis: S.B., Massachusetts Institute of Technology, Department of Mechanical Engineering, 2017. Cataloged from PDF version of thesis. Includes bibliographical references (page 26). The cytoskeleton is a crucial network of actin filaments that gives the cell its shape, assists in organelle organization, and allows for cell movement. Active muscle gels are a class of materials that that mimic the functionality of the cytoskeleton. Utilizing myosin II motor proteins to initiate contraction events in actin networks, active muscle gels have the unique potential of acting as microscopic actuators. Two challenges currently faced by active muscle gels are their slow contraction time and weak contraction forces. This thesis seeks to achieve contraction events in a lab setting and observe how contraction speed and extent varies with the concentration of myosin motors and alpha-actinin crosslinks. by Joseph M. Babcock. S.B. 2017-12-05T19:18:33Z 2017-12-05T19:18:33Z 2017 2017 Thesis http://hdl.handle.net/1721.1/112565 1013187538 eng MIT theses are protected by copyright. They may be viewed, downloaded, or printed from this source but further reproduction or distribution in any format is prohibited without written permission. http://dspace.mit.edu/handle/1721.1/7582 26 pages application/pdf Massachusetts Institute of Technology |
| spellingShingle | Mechanical Engineering. Babcock, Joseph M. (Joseph Michel) Effects of cross-link and myosin motor concentrations on active muscle gel contraction time and extent |
| title | Effects of cross-link and myosin motor concentrations on active muscle gel contraction time and extent |
| title_full | Effects of cross-link and myosin motor concentrations on active muscle gel contraction time and extent |
| title_fullStr | Effects of cross-link and myosin motor concentrations on active muscle gel contraction time and extent |
| title_full_unstemmed | Effects of cross-link and myosin motor concentrations on active muscle gel contraction time and extent |
| title_short | Effects of cross-link and myosin motor concentrations on active muscle gel contraction time and extent |
| title_sort | effects of cross link and myosin motor concentrations on active muscle gel contraction time and extent |
| topic | Mechanical Engineering. |
| url | http://hdl.handle.net/1721.1/112565 |
| work_keys_str_mv | AT babcockjosephmjosephmichel effectsofcrosslinkandmyosinmotorconcentrationsonactivemusclegelcontractiontimeandextent |