Disrupted in schizophrenia 1 (DISC1) L100P mutants have impaired activity-dependent plasticity in vivo and in vitro

Disrupted in schizophrenia 1 (DISC1) L100P mutants have impaired activity-dependent plasticity in vivo and in vitro

Major neuropsychiatric disorders are genetically complex but share overlapping etiology. Mice mutant for rare, highly penetrant risk variants can be useful in dissecting the molecular mechanisms involved. The gene disrupted in schizophrenia 1 (DISC1) has been associated with increased risk for neuro...

Full description

Bibliographic Details
Main Authors: Molinos, I, Petit, E, Bellini, S, O'Tuathaigh, C, Schorova, L, Mitchell, K J, Waddington, J, Gill, M, Corvin, A P, Tropea, Daniela, Nagakura, Ikue, Sur, Mriganka
Other Authors: Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences
Format: Article
Published: Nature Publishing Group 2017
Online Access:http://hdl.handle.net/1721.1/112610
https://orcid.org/0000-0001-9730-6636
https://orcid.org/0000-0003-2442-5671

Similar Items

Similar Items