What is memory? The present state of the engram
The mechanism of memory remains one of the great unsolved problems of biology. Grappling with the question more than a hundred years ago, the German zoologist Richard Semon formulated the concept of the engram, lasting connections in the brain that result from simultaneous "excitations", w...
| Main Authors: | , , , , , , , , , , , , , , , , , , |
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| Format: | Article |
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Biomed Central Ltd.
2017
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| Online Access: | http://hdl.handle.net/1721.1/112681 https://orcid.org/0000-0003-0121-8514 https://orcid.org/0000-0003-2839-8228 https://orcid.org/0000-0003-1262-0592 |
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| author | Poo, Mu-ming Bonhoeffer, Tobias Martin, Kelsey C. Tsien, Richard W. Fishell, Gord Mullins, Caitlin Gonçalves, J. Tiago Shtrahman, Matthew Johnston, Stephen T. Gage, Fred H. Dan, Yang Long, John Buzsáki, György Stevens, Charles Pignatelli di Spinazzola, Michele Ryan, Tomas John Tonegawa, Susumu Rudenko, Andrii Tsai, Li-Huei |
| author2 | Massachusetts Institute of Technology. Department of Biology |
| author_facet | Massachusetts Institute of Technology. Department of Biology Poo, Mu-ming Bonhoeffer, Tobias Martin, Kelsey C. Tsien, Richard W. Fishell, Gord Mullins, Caitlin Gonçalves, J. Tiago Shtrahman, Matthew Johnston, Stephen T. Gage, Fred H. Dan, Yang Long, John Buzsáki, György Stevens, Charles Pignatelli di Spinazzola, Michele Ryan, Tomas John Tonegawa, Susumu Rudenko, Andrii Tsai, Li-Huei |
| author_sort | Poo, Mu-ming |
| collection | MIT |
| description | The mechanism of memory remains one of the great unsolved problems of biology. Grappling with the question more than a hundred years ago, the German zoologist Richard Semon formulated the concept of the engram, lasting connections in the brain that result from simultaneous "excitations", whose precise physical nature and consequences were out of reach of the biology of his day. Neuroscientists now have the knowledge and tools to tackle this question, however, and this Forum brings together leading contemporary views on the mechanisms of memory and what the engram means today. |
| first_indexed | 2024-09-23T09:03:46Z |
| format | Article |
| id | mit-1721.1/112681 |
| institution | Massachusetts Institute of Technology |
| last_indexed | 2024-09-23T09:03:46Z |
| publishDate | 2017 |
| publisher | Biomed Central Ltd. |
| record_format | dspace |
| spelling | mit-1721.1/1126812022-09-26T10:12:52Z What is memory? The present state of the engram Poo, Mu-ming Bonhoeffer, Tobias Martin, Kelsey C. Tsien, Richard W. Fishell, Gord Mullins, Caitlin Gonçalves, J. Tiago Shtrahman, Matthew Johnston, Stephen T. Gage, Fred H. Dan, Yang Long, John Buzsáki, György Stevens, Charles Pignatelli di Spinazzola, Michele Ryan, Tomas John Tonegawa, Susumu Rudenko, Andrii Tsai, Li-Huei Massachusetts Institute of Technology. Department of Biology Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences Picower Institute for Learning and Memory Pignatelli di Spinazzola, Michele Ryan, Tomas John Tonegawa, Susumu Rudenko, Andrii Tsai, Li-Huei The mechanism of memory remains one of the great unsolved problems of biology. Grappling with the question more than a hundred years ago, the German zoologist Richard Semon formulated the concept of the engram, lasting connections in the brain that result from simultaneous "excitations", whose precise physical nature and consequences were out of reach of the biology of his day. Neuroscientists now have the knowledge and tools to tackle this question, however, and this Forum brings together leading contemporary views on the mechanisms of memory and what the engram means today. 2017-12-11T15:23:12Z 2017-12-11T15:23:12Z 2016-05 2017-12-11T13:28:40Z Article http://purl.org/eprint/type/JournalArticle 1741-7007 http://hdl.handle.net/1721.1/112681 Poo, Mu-ming et al. “What Is Memory? The Present State of the Engram.” BMC Biology 14, 1 (May 2016) © 2016 Poo et al https://orcid.org/0000-0003-0121-8514 https://orcid.org/0000-0003-2839-8228 https://orcid.org/0000-0003-1262-0592 http://dx.doi.org/10.1186/S12915-016-0261-6 BMC Biology Article is made available in accordance with the publisher's policy and may be subject to US copyright law. Please refer to the publisher's site for terms of use. application/pdf Biomed Central Ltd. BioMedCentral |
| spellingShingle | Poo, Mu-ming Bonhoeffer, Tobias Martin, Kelsey C. Tsien, Richard W. Fishell, Gord Mullins, Caitlin Gonçalves, J. Tiago Shtrahman, Matthew Johnston, Stephen T. Gage, Fred H. Dan, Yang Long, John Buzsáki, György Stevens, Charles Pignatelli di Spinazzola, Michele Ryan, Tomas John Tonegawa, Susumu Rudenko, Andrii Tsai, Li-Huei What is memory? The present state of the engram |
| title | What is memory? The present state of the engram |
| title_full | What is memory? The present state of the engram |
| title_fullStr | What is memory? The present state of the engram |
| title_full_unstemmed | What is memory? The present state of the engram |
| title_short | What is memory? The present state of the engram |
| title_sort | what is memory the present state of the engram |
| url | http://hdl.handle.net/1721.1/112681 https://orcid.org/0000-0003-0121-8514 https://orcid.org/0000-0003-2839-8228 https://orcid.org/0000-0003-1262-0592 |
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