Angiotensin II-derived constrained peptides with antiplasmodial activity and suppressed vasoconstriction
Angiotensin II (Ang II) is a natural mammalian hormone that has been described to exhibit antiplasmodial activity therefore constituting a promising alternative for the treatment of malaria. Despite its promise, the development of Ang II as an antimalarial is limited by its potent induction of vasoc...
Main Authors: | Silva, Adriana Farias, Silva, Leandro Souza, Alves, Flavio Lopes, de Sá Pinheiro, Ana Acácia, Miranda, Antonio, Capurro, Margareth Lara, Oliveira, Vani Xavier, Der Torossian Torres, Marcelo, de la Fuente Nunez, Cesar |
---|---|
Other Authors: | MIT Synthetic Biology Center |
Format: | Article |
Published: |
Nature Publishing Group
2017
|
Online Access: | http://hdl.handle.net/1721.1/112690 |
Similar Items
-
Synthetic Host Defense Peptides Inhibit Venezuelan Equine Encephalitis Virus Replication and the Associated Inflammatory Response
by: Ahmed, Aslaa, et al.
Published: (2022) -
Engineering Phage Host-Range and Suppressing Bacterial Resistance through Phage Tail Fiber Mutagenesis
by: Yehl, Kevin, et al.
Published: (2021) -
Synthetic Host Defense Peptides Inhibit Venezuelan Equine Encephalitis Virus Replication and the Associated Inflammatory Response
by: Ahmed, Aslaa, et al.
Published: (2021) -
Next-generation precision antimicrobials: towards personalized treatment of infectious diseases
by: de la Fuente Nunez, Cesar, et al.
Published: (2019) -
Deep generative models for peptide design
by: Wan, Fangping, et al.
Published: (2022)