Calcified plaque modification alters local drug delivery in the treatment of peripheral atherosclerosis

Calcified plaque modification alters local drug delivery in the treatment of peripheral atherosclerosis

Background: Calcific atherosclerosis is a major challenge to intraluminal drug delivery in peripheral artery disease (PAD). Objectives: We evaluated the effects of orbital atherectomy on intraluminal paclitaxel delivery to human peripheral arteries with substantial calcified plaque. Methods: Diagnos...

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Bibliographic Details
Main Authors:	Zani, Brett, Stanley, James, Muraj, Benny, Knutson, Jennifer, Kohler, Robert, Markham, Peter, Nikanorov, Alexander, Tzafriri, A Rami, Garcia Polite, Fernando, Edelman, Elazer R
Other Authors:	Massachusetts Institute of Technology. Institute for Medical Engineering & Science
Format:	Article
Published:	Elsevier 2017
Online Access:	http://hdl.handle.net/1721.1/112760 https://orcid.org/0000-0002-7832-7156

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