Modeling chromosomes: Beyond pretty pictures

Recently, Chromosome Conformation Capture (3C) based experiments have highlighted the importance of computational models for the study of chromosome organization. In this review, we propose that current computational models can be grouped into roughly four classes, with two classes of data-driven mo...

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Bibliographic Details
Main Authors: Imakaev, Maksim Viktorovich, Fudenberg, Geoffrey, Mirny, Leonid A
Other Authors: Institute for Medical Engineering and Science
Format: Article
Published: Elsevier 2017
Online Access:http://hdl.handle.net/1721.1/112798
https://orcid.org/0000-0002-5320-2728
https://orcid.org/0000-0001-5905-6517
https://orcid.org/0000-0002-0785-5410