Methods of Blood Pressure Measurement in the ICU*
OBJECTIVE:: Minimal clinical research has investigated the significance of different blood pressure monitoring techniques in the ICU and whether systolic vs. mean blood pressures should be targeted in therapeutic protocols and in defining clinical study cohorts. The objectives of this study are to c...
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| Format: | Article |
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Wolters Kluwer - Lippincott Williams & Wilkins
2017
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| Online Access: | http://hdl.handle.net/1721.1/112806 https://orcid.org/0000-0002-6318-2978 |
| _version_ | 1826213563086143488 |
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| author | Talmor, Daniel Malhotra, Atul Lehman, Li-Wei Saeed, Mohammed Mark, Roger G |
| author2 | Massachusetts Institute of Technology. Institute for Medical Engineering & Science |
| author_facet | Massachusetts Institute of Technology. Institute for Medical Engineering & Science Talmor, Daniel Malhotra, Atul Lehman, Li-Wei Saeed, Mohammed Mark, Roger G |
| author_sort | Talmor, Daniel |
| collection | MIT |
| description | OBJECTIVE:: Minimal clinical research has investigated the significance of different blood pressure monitoring techniques in the ICU and whether systolic vs. mean blood pressures should be targeted in therapeutic protocols and in defining clinical study cohorts. The objectives of this study are to compare real-world invasive arterial blood pressure with noninvasive blood pressure, and to determine if differences between the two techniques have clinical implications. DESIGN:: We conducted a retrospective study comparing invasive arterial blood pressure and noninvasive blood pressure measurements using a large ICU database. We performed pairwise comparison between concurrent measures of invasive arterial blood pressure and noninvasive blood pressure. We studied the association of systolic and mean invasive arterial blood pressure and noninvasive blood pressure with acute kidney injury, and with ICU mortality. SETTING:: Adult intensive care units at a tertiary care hospital. PATIENTS:: Adult patients admitted to intensive care units between 2001 and 2007. INTERVENTIONS:: None. MEASUREMENTS AND MAIN RESULTS:: Pairwise analysis of 27,022 simultaneously measured invasive arterial blood pressure/noninvasive blood pressure pairs indicated that noninvasive blood pressure overestimated systolic invasive arterial blood pressure during hypotension. Analysis of acute kidney injury and ICU mortality involved 1,633 and 4,957 patients, respectively. Our results indicated that hypotensive systolic noninvasive blood pressure readings were associated with a higher acute kidney injury prevalence (p = 0.008) and ICU mortality (p < 0.001) than systolic invasive arterial blood pressure in the same range (≤70 mm Hg). Noninvasive blood pressure and invasive arterial blood pressure mean arterial pressures showed better agreement; acute kidney injury prevalence (p = 0.28) and ICU mortality (p = 0.76) associated with hypotensive mean arterial pressure readings (≤60 mm Hg) were independent of measurement technique. CONCLUSIONS:: Clinically significant discrepancies exist between invasive and noninvasive systolic blood pressure measurements during hypotension. Mean blood pressure from both techniques may be interpreted in a consistent manner in assessing patients' prognosis. Our results suggest that mean rather than systolic blood pressure is the pre ferred metric in the ICU to guide therapy. |
| first_indexed | 2024-09-23T15:51:14Z |
| format | Article |
| id | mit-1721.1/112806 |
| institution | Massachusetts Institute of Technology |
| last_indexed | 2024-09-23T15:51:14Z |
| publishDate | 2017 |
| publisher | Wolters Kluwer - Lippincott Williams & Wilkins |
| record_format | dspace |
| spelling | mit-1721.1/1128062022-10-02T04:38:36Z Methods of Blood Pressure Measurement in the ICU* Talmor, Daniel Malhotra, Atul Lehman, Li-Wei Saeed, Mohammed Mark, Roger G Massachusetts Institute of Technology. Institute for Medical Engineering & Science Harvard University--MIT Division of Health Sciences and Technology Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science Lehman, Li-Wei Saeed, Mohammed Mark, Roger G OBJECTIVE:: Minimal clinical research has investigated the significance of different blood pressure monitoring techniques in the ICU and whether systolic vs. mean blood pressures should be targeted in therapeutic protocols and in defining clinical study cohorts. The objectives of this study are to compare real-world invasive arterial blood pressure with noninvasive blood pressure, and to determine if differences between the two techniques have clinical implications. DESIGN:: We conducted a retrospective study comparing invasive arterial blood pressure and noninvasive blood pressure measurements using a large ICU database. We performed pairwise comparison between concurrent measures of invasive arterial blood pressure and noninvasive blood pressure. We studied the association of systolic and mean invasive arterial blood pressure and noninvasive blood pressure with acute kidney injury, and with ICU mortality. SETTING:: Adult intensive care units at a tertiary care hospital. PATIENTS:: Adult patients admitted to intensive care units between 2001 and 2007. INTERVENTIONS:: None. MEASUREMENTS AND MAIN RESULTS:: Pairwise analysis of 27,022 simultaneously measured invasive arterial blood pressure/noninvasive blood pressure pairs indicated that noninvasive blood pressure overestimated systolic invasive arterial blood pressure during hypotension. Analysis of acute kidney injury and ICU mortality involved 1,633 and 4,957 patients, respectively. Our results indicated that hypotensive systolic noninvasive blood pressure readings were associated with a higher acute kidney injury prevalence (p = 0.008) and ICU mortality (p < 0.001) than systolic invasive arterial blood pressure in the same range (≤70 mm Hg). Noninvasive blood pressure and invasive arterial blood pressure mean arterial pressures showed better agreement; acute kidney injury prevalence (p = 0.28) and ICU mortality (p = 0.76) associated with hypotensive mean arterial pressure readings (≤60 mm Hg) were independent of measurement technique. CONCLUSIONS:: Clinically significant discrepancies exist between invasive and noninvasive systolic blood pressure measurements during hypotension. Mean blood pressure from both techniques may be interpreted in a consistent manner in assessing patients' prognosis. Our results suggest that mean rather than systolic blood pressure is the pre ferred metric in the ICU to guide therapy. National Institute of Biomedical Imaging and Bioengineering (U.S.) (Grant R01EB001659) 2017-12-19T18:26:08Z 2017-12-19T18:26:08Z 2013-01 2017-12-19T16:05:16Z Article http://purl.org/eprint/type/JournalArticle 0090-3493 http://hdl.handle.net/1721.1/112806 Lehman, Li-wei H. et al. “Methods of Blood Pressure Measurement in the ICU*.” Critical Care Medicine 41, 1 (January 2013): 34–40 © 2013 by the Society of Critical Care Medicine and Lippincott Williams & Wilkins https://orcid.org/0000-0002-6318-2978 http://dx.doi.org/10.1097/CCM.0b013e318265ea46 Critical Care Medicine Creative Commons Attribution-Noncommercial-Share Alike http://creativecommons.org/licenses/by-nc-sa/4.0/ application/pdf Wolters Kluwer - Lippincott Williams & Wilkins PMC |
| spellingShingle | Talmor, Daniel Malhotra, Atul Lehman, Li-Wei Saeed, Mohammed Mark, Roger G Methods of Blood Pressure Measurement in the ICU* |
| title | Methods of Blood Pressure Measurement in the ICU* |
| title_full | Methods of Blood Pressure Measurement in the ICU* |
| title_fullStr | Methods of Blood Pressure Measurement in the ICU* |
| title_full_unstemmed | Methods of Blood Pressure Measurement in the ICU* |
| title_short | Methods of Blood Pressure Measurement in the ICU* |
| title_sort | methods of blood pressure measurement in the icu |
| url | http://hdl.handle.net/1721.1/112806 https://orcid.org/0000-0002-6318-2978 |
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