Development of a Method for the N-Arylation of Amino Acid Esters with Aryl Triflates
A general method for the N-arylation of amino acid esters with aryl triflates is described. Both α- and β-amino acid esters, including methyl, tert-butyl, and benzyl esters, are viable substrates. Reaction optimization was carried out by design of experiment (DOE) analysis using JMP software. The mi...
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| Format: | Article |
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American Chemical Society (ACS)
2018
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| Online Access: | http://hdl.handle.net/1721.1/113054 https://orcid.org/0000-0003-4301-8326 https://orcid.org/0000-0003-3875-4775 |