Proteolytic control of the mitochondrial calcium uniporter complex
The mitochondrial calcium uniporter is a Ca²⁺-activated Ca²⁺ channel complex mediating mitochondrial Ca²⁺ uptake, a process crucial for Ca²⁺ signaling, bioenergetics, and cell death. The uniporter is composed of the pore-forming MCU protein, the gatekeeping MICU1 and MICU2 subunits, and EMRE, a sing...
Main Authors: | , , , , , , , |
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Format: | Article |
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National Academy of Sciences (U.S.)
2018
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Online Access: | http://hdl.handle.net/1721.1/113225 https://orcid.org/0000-0001-6788-7185 |