Proteolytic control of the mitochondrial calcium uniporter complex

The mitochondrial calcium uniporter is a Ca²⁺-activated Ca²⁺ channel complex mediating mitochondrial Ca²⁺ uptake, a process crucial for Ca²⁺ signaling, bioenergetics, and cell death. The uniporter is composed of the pore-forming MCU protein, the gatekeeping MICU1 and MICU2 subunits, and EMRE, a sing...

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Bibliographic Details
Main Authors: Tsai, Chen-Wei, Wu, Yujiao, Pao, Ping-Chieh, Phillips, Charles B., Williams, Carole, Miller, Christopher, Ranaghan, Matthew, Tsai, Ming-Feng
Other Authors: Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences
Format: Article
Published: National Academy of Sciences (U.S.) 2018
Online Access:http://hdl.handle.net/1721.1/113225
https://orcid.org/0000-0001-6788-7185