Solid-State NMR Investigation of the Conformation, Proton Conduction, and Hydration of the Influenza B Virus M2 Transmembrane Proton Channel
Together with the influenza A virus, influenza B virus causes seasonal flu epidemics. The M2 protein of influenza B (BM2) forms a tetrameric proton-conducting channel that is important for the virus lifecycle. BM2 shares little sequence homology with AM2, except for a conserved HxxxW motif in the tr...
Main Authors: | Wang, Jun, Williams, Jonathan Kyle, Tietze, Daniel, Lee, Myungwoon, Hong, Mei |
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Other Authors: | Massachusetts Institute of Technology. Department of Chemistry |
Format: | Article |
Published: |
American Chemical Society (ACS)
2018
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Online Access: | http://hdl.handle.net/1721.1/113320 https://orcid.org/0000-0002-7272-6885 https://orcid.org/0000-0003-3002-6298 https://orcid.org/0000-0001-5255-5858 |
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