Ensemble Kinetic Modeling of Metabolic Networks from Dynamic Metabolic Profiles

Ensemble Kinetic Modeling of Metabolic Networks from Dynamic Metabolic Profiles

Kinetic modeling of metabolic pathways has important applications in metabolic engineering, but significant challenges still remain. The difficulties faced vary from finding best-fit parameters in a highly multidimensional search space to incomplete parameter identifiability. To meet some of these c...

Full description

Bibliographic Details
Main Authors:	Jia, Gengjie, Stephanopoulos, Gregory, Gunawan, Rudiyanto
Other Authors:	Massachusetts Institute of Technology. Department of Chemical Engineering
Format:	Article
Published:	MDPI AG 2018
Online Access:	http://hdl.handle.net/1721.1/113357 https://orcid.org/0000-0001-6909-4568

Similar Items

Incremental parameter estimation of kinetic metabolic network models
by: Jia, Gengjie, et al.
Published: (2013)

Expanding the concepts and tools of metabolic engineering to elucidate cancer metabolism
by: Fendt, Sarah-Maria, et al.
Published: (2014)

Review of methods to probe single cell metabolism and bioenergetics
by: Vasdekis, Andreas E., et al.
Published: (2016)

Improving fatty acids production by engineering dynamic pathway regulation and metabolic control
by: Xu, Peng, et al.
Published: (2015)

Simple glycolipids of microbes: Chemistry, biological activity and metabolic engineering
by: Abdel-Mawgoud, Ahmad Mohammad, et al.
Published: (2021)

Simple glycolipids of microbes: Chemistry, biological activity and metabolic engineering
by: Abdel-Mawgoud, Ahmad Mohammad, et al.
Published: (2022)

A metabolic profiling approach to human disorders of energy metabolism
by: Shaham, Oded
Published: (2010)

Dynamic metabolic networks: going with the flow.
by: Kruger, N, et al.
Published: (2007)

A Functional Protein Chip for Combinatorial Pathway Optimization and In Vitro Metabolic Engineering
by: Jung, Gyoo Yeol, et al.
Published: (2003)

Quantifying redox metabolism in the plant metabolic network
by: Smith, E
Published: (2021)

A Review of Large-Scale Kinetic Parameters in Metabolic Network Model of Escherichia coli
by: Azrag, M. A. K., et al.
Published: (2018)

Metabolic requirements for cancer cell proliferation
by: Iliopoulos, Othon, et al.
Published: (2018)

Application of metabolic controls for the maximization of lipid production in semicontinuous fermentation
by: Xu, Jingyang, et al.
Published: (2018)

A hybrid kinetic and constraint-based model of leaf metabolism allows predictions of metabolic fluxes in different environments
by: Shameer, S, et al.
Published: (2021)

Piecewise multivariate modelling of sequential metabolic profiling data
by: Rantalainen, M, et al.
Published: (2008)

Inverse Metabolic Engineering of Synechocystis PCC 6803 for Improved Growth Rate and Poly-3-hydroxybutyrate Production
by: Tyo, Keith E., et al.
Published: (2004)

Compartmentalization of metabolic pathways in yeast mitochondria improves the production of branched-chain alcohols
by: Stephanopoulos, Gregory, et al.
Published: (2014)

Accessing Nature’s diversity through metabolic engineering and synthetic biology
by: King, Jason R, et al.
Published: (2017)

METABOLIC PROFILES AFTER PANCREAS TRANSPLANTATION
by: Mittal, S, et al.
Published: (2013)

Large-scale Kinetic Parameter Identification of Metabolic Network Model of E. coli using PSO
by: Azrag, M. A. K., et al.
Published: (2015)

Insights into plant metabolic networks from steady-state metabolic flux analysis.
by: Kruger, N, et al.
Published: (2009)

Insights into plant metabolic networks from steady-state metabolic flux analysis.
by: Kruger, N, et al.
Published: (2009)

Kinetic paramaters identification for large-scle metabolic model of escherichia coli
by: Mohammed Adam, Kunna Azrag
Published: (2015)

Large-scale kinetic parameters estimation of metabolic model of escherichia coli
by: Azrag, M. A. K., et al.
Published: (2019)

Segment Particle Swarm Optimization Adoption for Large-Scale Kinetic Parameter Identification of Metabolic Network Model
by: Azrag, M. A. K., et al.
Published: (2018)

Dynamic modeling of type 1 diabetic metabolism
by: Jivesh Ramduny
Published: (2015)

Lipidomic profiling identifies signatures of metabolic risk
by: Yin, X, et al.
Published: (2019)

Optimization of [superscript 13]C isotopic tracers for metabolic flux analysis in mammalian cells
by: Walther, Jason L., et al.
Published: (2015)

The dynamics and control of glucose metabolism.
by: Hillman, Robert Steven
Published: (2005)

Metabolic modeling software for metabolic assessment of diabetic patients
by: Lee, Chew Tin, et al.
Published: (2008)

Regulation of metabolic networks: understanding metabolic complexity in the systems biology era.
by: Sweetlove, L, et al.
Published: (2005)

The future of metabolic engineering and synthetic biology: Towards a systematic practice
by: Yadav, Vikramaditya G., et al.
Published: (2015)

Inferring Carbon Sources from Gene Expression Profiles Using Metabolic Flux Models
by: Brandes, Aaron, et al.
Published: (2012)

Nutrient gradients in engineered cartilage: metabolic kinetics measurement and mass transfer modeling.
by: Zhou, S, et al.
Published: (2008)

Metabolic Network Analysis Demystified
by: Chindelevitch, Leonid, et al.
Published: (2013)

The dynamic interplay between DNA damage and metabolism : the metabolic fate and transport of DNA lesions and novel DNA damage derived from intermediary metabolism
by: Jumpathong, Watthanachai
Published: (2015)

Distributing a metabolic pathway among a microbial consortium enhances production of natural products
by: Zhou, Kang, et al.
Published: (2016)

Partitioning metabolism between growth and product synthesis for coordinated production of wax esters in Acinetobacter baylyi ADP1
by: Santala, Suvi, et al.
Published: (2022)

Fat metabolism and the metabolic syndrome
by: Bickerton, A, et al.
Published: (2008)

Skeletal blood flow and calcium kinetics in metabolic bone disease.
by: Wootton, R, et al.
Published: (1977)