Readily accessible multifunctional fluorous emulsions
Strategies for the facile fabrication of nanoscale materials and devices represent an increasingly important challenge for chemists. Here, we report a simple, one-pot procedure for the formation of perfluorocarbon emulsions with defined functionalization. The fluorous core allows for small molecules...
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| Format: | Article |
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Royal Society of Chemistry (RSC)
2018
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| Online Access: | http://hdl.handle.net/1721.1/113584 |
| _version_ | 1826215241028993024 |
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| author | Sletten, Ellen M. Swager, Timothy M |
| author2 | Massachusetts Institute of Technology. Department of Chemistry |
| author_facet | Massachusetts Institute of Technology. Department of Chemistry Sletten, Ellen M. Swager, Timothy M |
| author_sort | Sletten, Ellen M. |
| collection | MIT |
| description | Strategies for the facile fabrication of nanoscale materials and devices represent an increasingly important challenge for chemists. Here, we report a simple, one-pot procedure for the formation of perfluorocarbon emulsions with defined functionalization. The fluorous core allows for small molecules containing a fluorous tail to be stabilized inside the emulsions. The emulsions can be formed using a variety of hydrophilic polymers resulting in an array of sizes (90 nm to > 1 micron) and surface charges (-95 mV to 65 mV) of fluid particles. The surface of the emulsions can be further functionalized, covalently or non-covalently, through in situ or post-emulsion modification. The total preparation time is 30 minutes or less from commercially available reagents without specialized equipment. We envision these emulsions to be applicable to both biological and materials systems. |
| first_indexed | 2024-09-23T16:19:53Z |
| format | Article |
| id | mit-1721.1/113584 |
| institution | Massachusetts Institute of Technology |
| last_indexed | 2024-09-23T16:19:53Z |
| publishDate | 2018 |
| publisher | Royal Society of Chemistry (RSC) |
| record_format | dspace |
| spelling | mit-1721.1/1135842022-10-02T07:45:57Z Readily accessible multifunctional fluorous emulsions Sletten, Ellen M. Swager, Timothy M Massachusetts Institute of Technology. Department of Chemistry Sletten, Ellen M. Swager, Timothy M Strategies for the facile fabrication of nanoscale materials and devices represent an increasingly important challenge for chemists. Here, we report a simple, one-pot procedure for the formation of perfluorocarbon emulsions with defined functionalization. The fluorous core allows for small molecules containing a fluorous tail to be stabilized inside the emulsions. The emulsions can be formed using a variety of hydrophilic polymers resulting in an array of sizes (90 nm to > 1 micron) and surface charges (-95 mV to 65 mV) of fluid particles. The surface of the emulsions can be further functionalized, covalently or non-covalently, through in situ or post-emulsion modification. The total preparation time is 30 minutes or less from commercially available reagents without specialized equipment. We envision these emulsions to be applicable to both biological and materials systems. National Science Foundation (U.S.) (Award CCS-0939514) 2018-02-12T16:42:23Z 2018-02-12T16:42:23Z 2016-04 2016-01 2018-02-08T18:06:37Z Article http://purl.org/eprint/type/JournalArticle 2041-6520 2041-6539 http://hdl.handle.net/1721.1/113584 Sletten, Ellen M., and Swager, Timothy M. “Readily Accessible Multifunctional Fluorous Emulsions.” Chemical Science 7, 8 (2016): 5091–5097 © 2016 The Royal Society of Chemistry http://dx.doi.org/10.1039/C6SC00341A Chemical Science Creative Commons Attribution 3.0 Unported license http://creativecommons.org/licenses/by/3.0/ application/pdf Royal Society of Chemistry (RSC) Royal Society of Chemistry |
| spellingShingle | Sletten, Ellen M. Swager, Timothy M Readily accessible multifunctional fluorous emulsions |
| title | Readily accessible multifunctional fluorous emulsions |
| title_full | Readily accessible multifunctional fluorous emulsions |
| title_fullStr | Readily accessible multifunctional fluorous emulsions |
| title_full_unstemmed | Readily accessible multifunctional fluorous emulsions |
| title_short | Readily accessible multifunctional fluorous emulsions |
| title_sort | readily accessible multifunctional fluorous emulsions |
| url | http://hdl.handle.net/1721.1/113584 |
| work_keys_str_mv | AT slettenellenm readilyaccessiblemultifunctionalfluorousemulsions AT swagertimothym readilyaccessiblemultifunctionalfluorousemulsions |