A Reproducibility-Based Computational Framework Identifies an Inducible, Enhanced Antiviral State in Dendritic Cells from HIV-1 Elite Controllers

A Reproducibility-Based Computational Framework Identifies an Inducible, Enhanced Antiviral State in Dendritic Cells from HIV-1 Elite Controllers

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Background Human immunity relies on the coordinated responses of many cellular subsets and functional states. Inter-individual variations in cellular composition and communication could thus potentially alter host protection. Here, we explore this hypothesis by applying single-cell RNA-sequencing t...

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Bibliographic Details
Main Authors: Martin-Gayo, Enrique, Ouyang, Zhengyu, Cronin, Jacqueline, Lichterfeld, Mathias, Yosef, Nir, Cole, Michael B., Walker, Bruce D., Yu, Xu G., Kolb, Kellie Elizabeth, Kazer, Samuel Weisgurt, Ordovas-Montanes, Jose Manuel, Shalek, Alexander K
Other Authors: Massachusetts Institute of Technology. Institute for Medical Engineering & Science
Format: Article
Language:English
Published: Biomed Central Ltd. 2018
Online Access:http://hdl.handle.net/1721.1/113611
https://orcid.org/0000-0003-0710-7305
https://orcid.org/0000-0002-7380-9594

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