Structure of the human TRiC/CCT Subunit 5 associated with hereditary sensory neuropathy
The human chaperonin TRiC consists of eight non-identical subunits, and its protein-folding activity is critical for cellular health. Misfolded proteins are associated with many human diseases, such as amyloid diseases, cancer, and neuropathies, making TRiC a potential therapeutic target. A detailed...
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פורמט: | Article |
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Nature Publishing Group
2018
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גישה מקוונת: | http://hdl.handle.net/1721.1/113627 |