Isoform-Specific Expression and Feedback Regulation of E Protein TCF4 Control Dendritic Cell Lineage Specification

Isoform-Specific Expression and Feedback Regulation of E Protein TCF4 Control Dendritic Cell Lineage Specification

The cell fate decision between interferon-producing plasmacytoid DC (pDC) and antigen-presenting classical DC (cDC) is controlled by the E protein transcription factor TCF4 (E2-2). We report that TCF4 comprises two transcriptional isoforms, both of which are required for optimal pDC development in v...

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Bibliographic Details
Main Authors: Grajkowska, Lucja T., Ceribelli, Michele, Lau, Colleen M., Warren, Margaret E., Tiniakou, Ioanna, Nakandakari Higa, Sandra, Bunin, Anna, Haecker, Hans, Staudt, Louis M., Reizis, Boris, Mirny, Leonid A
Other Authors: Institute for Medical Engineering and Science
Format: Article
Published: Elsevier 2018
Online Access:http://hdl.handle.net/1721.1/113710
https://orcid.org/0000-0002-0785-5410

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