Lower incidence of myocardial infarction after smoke-free legislation enforcement in Chile

Objective: To evaluate the impact of a complete smoking ban in enclosed spaces on the incidence of acute myocardial infarction in Chile. Methods: The population-based study involved residents of urban areas, where 80% of the Chilean population live, aged 20 years or older who had a myocardial infarc...

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Main Authors: Nazzal, Carolina, Harris, Jeffrey E
Other Authors: Massachusetts Institute of Technology. Department of Economics
Format: Article
Published: WHO Press 2018
Online Access:http://hdl.handle.net/1721.1/113889
https://orcid.org/0000-0002-9749-3205
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author Nazzal, Carolina
Harris, Jeffrey E
author2 Massachusetts Institute of Technology. Department of Economics
author_facet Massachusetts Institute of Technology. Department of Economics
Nazzal, Carolina
Harris, Jeffrey E
author_sort Nazzal, Carolina
collection MIT
description Objective: To evaluate the impact of a complete smoking ban in enclosed spaces on the incidence of acute myocardial infarction in Chile. Methods: The population-based study involved residents of urban areas, where 80% of the Chilean population live, aged 20 years or older who had a myocardial infarction. Monthly myocardial infarction incidence and mortality rates at health-care facilities between January 2011 and December 2014 were derived from admission and mortality databases. Regression discontinuity methods were used to estimate the near-immediate impact on disease incidence of enforcing smoke-free legislation in March 2013. The same analysis was performed for ischaemic stroke, degenerative disc disease and colon cancer. Data on the concentration of fine respirable particulates were included in an additional analysis of myocardial infarction incidence in the Santiago metropolitan area. Results: The enforcement of smoke-free legislation was associated with an abrupt, near-immediate decline of 0.639 cases of myocardial infarction per 100 000 adults per month (95% confidence interval, CI: 0.242 to 1.036; relative decline: 7.8%). Similar declines were observed in men and women and in people aged over and under 70 years. However, enforcement of the legislation was not associated with a significant change in the rate of ischaemic stroke, degenerative disc disease or colon cancer. The abrupt decline in myocardial infarction incidence was also observed when data on fine respirable particulates were included in an analysis for Santiago. Conclusion: The enforcement of extensive smoke-free legislation in Chile was associated with an abrupt, near-immediate decline in the incidence of myocardial infarction.
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spelling mit-1721.1/1138892022-09-28T13:53:59Z Lower incidence of myocardial infarction after smoke-free legislation enforcement in Chile Nazzal, Carolina Harris, Jeffrey E Massachusetts Institute of Technology. Department of Economics Harris, Jeffrey E Objective: To evaluate the impact of a complete smoking ban in enclosed spaces on the incidence of acute myocardial infarction in Chile. Methods: The population-based study involved residents of urban areas, where 80% of the Chilean population live, aged 20 years or older who had a myocardial infarction. Monthly myocardial infarction incidence and mortality rates at health-care facilities between January 2011 and December 2014 were derived from admission and mortality databases. Regression discontinuity methods were used to estimate the near-immediate impact on disease incidence of enforcing smoke-free legislation in March 2013. The same analysis was performed for ischaemic stroke, degenerative disc disease and colon cancer. Data on the concentration of fine respirable particulates were included in an additional analysis of myocardial infarction incidence in the Santiago metropolitan area. Results: The enforcement of smoke-free legislation was associated with an abrupt, near-immediate decline of 0.639 cases of myocardial infarction per 100 000 adults per month (95% confidence interval, CI: 0.242 to 1.036; relative decline: 7.8%). Similar declines were observed in men and women and in people aged over and under 70 years. However, enforcement of the legislation was not associated with a significant change in the rate of ischaemic stroke, degenerative disc disease or colon cancer. The abrupt decline in myocardial infarction incidence was also observed when data on fine respirable particulates were included in an analysis for Santiago. Conclusion: The enforcement of extensive smoke-free legislation in Chile was associated with an abrupt, near-immediate decline in the incidence of myocardial infarction. 2018-02-26T19:54:32Z 2018-02-26T19:54:32Z 2017-08 2017-06 2018-02-23T17:05:34Z Article http://purl.org/eprint/type/JournalArticle 0042-9686 http://hdl.handle.net/1721.1/113889 Nazzal, Carolina, and Jeffrey E. Harris. “Lower Incidence of Myocardial Infarction after Smoke-Free Legislation Enforcement in Chile.” Bulletin of the World Health Organization, vol. 95, no. 10, Oct. 2017, pp. 674–82. © World Health Organization, https://orcid.org/0000-0002-9749-3205 http://dx.doi.org/10.2471/BLT.16.189894 Bulletin of the World Health Organization Creative Commons Attribution 3.0 IGO http://creativecommons.org/licenses/by/3.0/igo application/pdf WHO Press Woeld Health Organization
spellingShingle Nazzal, Carolina
Harris, Jeffrey E
Lower incidence of myocardial infarction after smoke-free legislation enforcement in Chile
title Lower incidence of myocardial infarction after smoke-free legislation enforcement in Chile
title_full Lower incidence of myocardial infarction after smoke-free legislation enforcement in Chile
title_fullStr Lower incidence of myocardial infarction after smoke-free legislation enforcement in Chile
title_full_unstemmed Lower incidence of myocardial infarction after smoke-free legislation enforcement in Chile
title_short Lower incidence of myocardial infarction after smoke-free legislation enforcement in Chile
title_sort lower incidence of myocardial infarction after smoke free legislation enforcement in chile
url http://hdl.handle.net/1721.1/113889
https://orcid.org/0000-0002-9749-3205
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