Engineering immunity : enhancing T Cell vaccines and combination immunotherapies for the treatment of cancer

Engineering immunity : enhancing T Cell vaccines and combination immunotherapies for the treatment of cancer

Thesis: Ph. D., Massachusetts Institute of Technology, Department of Biological Engineering, 2017.

Bibliographic Details
Main Author:	Moynihan, Kelly D. (Kelly Dare)
Other Authors:	Darrell J. Irvine.
Format:	Thesis
Language:	eng
Published:	Massachusetts Institute of Technology 2018
Subjects:	Biological Engineering.
Online Access:	http://hdl.handle.net/1721.1/113960

Similar Items

Roles for Innate Immunity in Combination Immunotherapies
by: Moynihan, Kelly Dare, et al.
Published: (2018)

Engineering New Approaches to Cancer Vaccines
by: Irvine, D. J., et al.
Published: (2017)

Temporally Programmed CD8α[superscrip +] DC Activation Enhances Combination Cancer Immunotherapy
by: Szeto, Gregory L., et al.
Published: (2017)

Yeast-based vaccine approaches to cancer immunotherapy
by: Howland, Shanshan W
Published: (2009)

Eradication of large established tumors in mice by combination immunotherapy that engages innate and adaptive immune responses
by: Cochran, Jennifer R, et al.
Published: (2017)

Fungal infections: immune defense, immunotherapies and vaccines
by: Loh, Jia Tong, et al.
Published: (2024)

Engineering more potent vaccines for the treatment of cancer and autoimmunity
by: Mehta, Naveen K.,Ph.D.Massachusetts Institute of Technology.
Published: (2019)

Engineering kinetics of immunotherapies and vaccines
by: Bhagchandani, Sachin Haresh
Published: (2024)

Integrin-targeted cancer immunotherapy
by: Kwan, Byron H. (Byron Hua)
Published: (2016)

Arming adoptively transferred T-cells with drug-loaded nanoparticles for cancer immunotherapy
by: Zheng, Yiran, Ph. D. Massachusetts Institute of Technology
Published: (2016)

Synergistic Innate and Adaptive Immune Response to Combination Immunotherapy with Anti-Tumor Antigen Antibodies and Extended Serum Half-Life IL-2
by: Surana, Rishi, et al.
Published: (2016)

T cell mediated combination immunotherapy
by: Opel, Cary F. (Cary Francis)
Published: (2017)

Improving methods for cytokine immunotherapy of cancer
by: Tzeng, Alice
Published: (2016)

Targeting the tight junction : immunotherapy of colon cancer
by: Ackerman, Margaret E
Published: (2011)

Combined HDAC and BET Inhibition Enhances Melanoma Vaccine Immunogenicity and Efficacy
by: Badamchi-Zadeh, Alexander, et al.
Published: (2020)

Applications of forward genetic screens to LncRNAs, cancer immunotherapy, and cellular engineering
by: Joung, Julia.
Published: (2021)

Rare-Earth Nanoparticles for Non-invasive In Vivo Imaging of Immune Cells in Cancer Immunotherapy
by: Kataria, Swati
Published: (2022)

Engineered Microphysiological Systems for Testing Effectiveness of Cell-Based Cancer Immunotherapies
by: Campisi, Marco, et al.
Published: (2022)

Integrin-targeted cancer immunotherapy elicits protective adaptive immune responses
by: Dranoff, Glenn, et al.
Published: (2018)

Synthetic Nanoparticles for Vaccines and Immunotherapy
by: Rakhra, Kavya, et al.
Published: (2017)

Sonodynamic cytokine nanocomplexes with specific stimulation towards effector T cell for combination cancer immunotherapy
by: Xu, Mengke, et al.
Published: (2023)

Targeting immune cells for cancer therapy
by: Gun, Sin Yee, et al.
Published: (2020)

Cancer-cell stiffening via cholesterol depletion enhances adoptive T-cell immunotherapy
by: Lei, Kewen, et al.
Published: (2022)

Investigation of T cell-mediated immune surveillance against tumor-specific antigens in genetically engineered mouse models of cancer
by: Du Page, Michel Justin Porter
Published: (2011)

Engineering persistent interleukin-2 for cancer immunotherapy
by: Gai, Shuning
Published: (2013)

In vivo generation of 'vaccination nodes' using injectable alginate hydrogels for cancer immunotherapy
by: Hori, Yuki
Published: (2010)

T cell-targeting nanoparticles focus delivery of immunotherapy to improve antitumor immunity
by: Schmid, Daniela, et al.
Published: (2018)

Tumor and immune reprogramming during immunotherapy in advanced renal cell carcinoma
Published: (2021)

Tumor and immune reprogramming during immunotherapy in advanced renal cell carcinoma
by: Regev, Aviv
Published: (2022)

Therapeutic effect of local hyperthermia treatment combined with anti-CD200 immunotherapy in EMT6 breast cancer
by: Wan Mohd Zawawi, Wan Fatin Amira
Published: (2023)

CRISPRi screens to identify combination therapies for the improved treatment of ovarian cancer
by: Handly, Erika Daphne.
Published: (2021)

Single cell landscape of innate and adaptive immunity in metastatic melanoma treated with immunotherapy
by: Fu, Ruiwen
Published: (2022)

Investigating immune surveillance, tolerance, and therapy in cancer
by: Cheung, Ann F
Published: (2009)

Delivering safer immunotherapies for cancer
by: Milling, Lauren Elizabeth, et al.
Published: (2018)

Microfluidic models for adoptive cell-mediated cancer immunotherapies
by: Adriani, Giulia, et al.
Published: (2018)

Engineering protein-based modulators of allergic, temporal, and checkpoint blockade anti-cancer immunity
by: Rothschilds, Adrienne Marie.
Published: (2019)

Financial viability and technical evaluation of dendritic cell-carrying "vaccination nodes" for immunotherapy
by: Song, Andrew, M. Eng. Massachusetts Institute of Technology
Published: (2009)

BiTEs and CAR-Ts : immunotherapy in childhood B-cell acute lymphoblastic leukemia
by: Besada, Rana Hany
Published: (2018)

Pharmacokinetic tuning of protein–antigen fusions enhances the immunogenicity of T-cell vaccines
by: Mehta, Naveen K, et al.
Published: (2021)

The promising immune checkpoint LAG-3 in cancer immunotherapy: from basic research to clinical application
by: Huo, Jin-Ling, et al.
Published: (2022)