Cancer-specific PERK signaling drives invasion and metastasis through CREB3L1

PERK signaling is required for cancer invasion and there is interest in targeting this pathway for therapy. Unfortunately, chemical inhibitors of PERK's kinase activity cause on-target side effects that have precluded their further development. One strategy for resolving this difficulty would b...

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Bibliographic Details
Main Authors: Feng, Yu-Xiong, Reinhardt, Ferenc, Jin, Dexter X., Sokol, Ethan Samuel, Miller, Daniel Handel, Gupta, Piyush
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Published: Nature Publishing Group 2018
Online Access:http://hdl.handle.net/1721.1/114663
https://orcid.org/0000-0003-1533-6730
https://orcid.org/0000-0002-2988-0537
https://orcid.org/0000-0002-4866-1145
https://orcid.org/0000-0002-9703-1780

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