Cancer-specific PERK signaling drives invasion and metastasis through CREB3L1
PERK signaling is required for cancer invasion and there is interest in targeting this pathway for therapy. Unfortunately, chemical inhibitors of PERK's kinase activity cause on-target side effects that have precluded their further development. One strategy for resolving this difficulty would b...
Main Authors: | Feng, Yu-Xiong, Reinhardt, Ferenc, Jin, Dexter X., Sokol, Ethan Samuel, Miller, Daniel Handel, Gupta, Piyush |
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Other Authors: | Massachusetts Institute of Technology. Department of Biology |
Format: | Article |
Published: |
Nature Publishing Group
2018
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Online Access: | http://hdl.handle.net/1721.1/114663 https://orcid.org/0000-0003-1533-6730 https://orcid.org/0000-0002-2988-0537 https://orcid.org/0000-0002-4866-1145 https://orcid.org/0000-0002-9703-1780 |
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