Design of a portable wide field of view GPU-accelerated multiphoton imaging system for real-time imaging of breast surgical specimens
We present a portable multiphoton system designed for evaluating centimeter-scale surgical margins on surgical breast specimens in a clinical setting. The system is designed to produce large field of view images at a high frame rate, while using GPU processing to render low latency, video-rate virtu...
| Main Authors: | , , , , , , , , , , , , |
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| Format: | Article |
| Language: | en_US |
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SPIE
2018
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| Online Access: | http://hdl.handle.net/1721.1/114749 https://orcid.org/0000-0002-2570-0770 https://orcid.org/0000-0003-4156-6484 https://orcid.org/0000-0003-3425-9486 https://orcid.org/0000-0003-4811-3429 https://orcid.org/0000-0002-0828-4357 |
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| author | Husvogt, Lennart Vardeh, Hilde Sheykin, Yury Faulkner-Jones, Beverly E. Hornegger, Joachim Brooker, Jeff Cable, Alex Connolly, James L. Giacomelli, Michael Yoshitake, Tadayuki Cahill, Lucas Christopher Ahsen, Osman Oguz Fujimoto, James G |
| author2 | Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science |
| author_facet | Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science Husvogt, Lennart Vardeh, Hilde Sheykin, Yury Faulkner-Jones, Beverly E. Hornegger, Joachim Brooker, Jeff Cable, Alex Connolly, James L. Giacomelli, Michael Yoshitake, Tadayuki Cahill, Lucas Christopher Ahsen, Osman Oguz Fujimoto, James G |
| author_sort | Husvogt, Lennart |
| collection | MIT |
| description | We present a portable multiphoton system designed for evaluating centimeter-scale surgical margins on surgical breast specimens in a clinical setting. The system is designed to produce large field of view images at a high frame rate, while using GPU processing to render low latency, video-rate virtual H&E images for real-time assessment. The imaging system and virtual H&E rendering algorithm are demonstrated by imaging unfixed human breast tissue in a clinical setting. |
| first_indexed | 2024-09-23T15:24:18Z |
| format | Article |
| id | mit-1721.1/114749 |
| institution | Massachusetts Institute of Technology |
| language | en_US |
| last_indexed | 2024-09-23T15:24:18Z |
| publishDate | 2018 |
| publisher | SPIE |
| record_format | dspace |
| spelling | mit-1721.1/1147492022-10-02T02:35:21Z Design of a portable wide field of view GPU-accelerated multiphoton imaging system for real-time imaging of breast surgical specimens Husvogt, Lennart Vardeh, Hilde Sheykin, Yury Faulkner-Jones, Beverly E. Hornegger, Joachim Brooker, Jeff Cable, Alex Connolly, James L. Giacomelli, Michael Yoshitake, Tadayuki Cahill, Lucas Christopher Ahsen, Osman Oguz Fujimoto, James G Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science Giacomelli, Michael Yoshitake, Tadayuki Cahill, Lucas Christopher Ahsen, Osman Oguz Fujimoto, James G We present a portable multiphoton system designed for evaluating centimeter-scale surgical margins on surgical breast specimens in a clinical setting. The system is designed to produce large field of view images at a high frame rate, while using GPU processing to render low latency, video-rate virtual H&E images for real-time assessment. The imaging system and virtual H&E rendering algorithm are demonstrated by imaging unfixed human breast tissue in a clinical setting. 2018-04-17T13:54:26Z 2018-04-17T13:54:26Z 2016-03 2016-02 Article http://purl.org/eprint/type/ConferencePaper 9781628419467 1605-7422 2410-9045 http://hdl.handle.net/1721.1/114749 Giacomelli, Michael G. et al. “Design of a Portable Wide Field of View GPU-Accelerated Multiphoton Imaging System for Real-Time Imaging of Breast Surgical Specimens.” Multiphoton Microscopy in the Biomedical Sciences XVI, February 2016, San Francisco, California, USA, edited by Ammasi Periasamy, Peter T. C. So, and Karsten König, SPIE, March 2016 https://orcid.org/0000-0002-2570-0770 https://orcid.org/0000-0003-4156-6484 https://orcid.org/0000-0003-3425-9486 https://orcid.org/0000-0003-4811-3429 https://orcid.org/0000-0002-0828-4357 en_US http://dx.doi.org/10.1117/12.2209241 Multiphoton Microscopy in the Biomedical Sciences XVI Article is made available in accordance with the publisher's policy and may be subject to US copyright law. Please refer to the publisher's site for terms of use. application/pdf SPIE SPIE |
| spellingShingle | Husvogt, Lennart Vardeh, Hilde Sheykin, Yury Faulkner-Jones, Beverly E. Hornegger, Joachim Brooker, Jeff Cable, Alex Connolly, James L. Giacomelli, Michael Yoshitake, Tadayuki Cahill, Lucas Christopher Ahsen, Osman Oguz Fujimoto, James G Design of a portable wide field of view GPU-accelerated multiphoton imaging system for real-time imaging of breast surgical specimens |
| title | Design of a portable wide field of view GPU-accelerated multiphoton imaging system for real-time imaging of breast surgical specimens |
| title_full | Design of a portable wide field of view GPU-accelerated multiphoton imaging system for real-time imaging of breast surgical specimens |
| title_fullStr | Design of a portable wide field of view GPU-accelerated multiphoton imaging system for real-time imaging of breast surgical specimens |
| title_full_unstemmed | Design of a portable wide field of view GPU-accelerated multiphoton imaging system for real-time imaging of breast surgical specimens |
| title_short | Design of a portable wide field of view GPU-accelerated multiphoton imaging system for real-time imaging of breast surgical specimens |
| title_sort | design of a portable wide field of view gpu accelerated multiphoton imaging system for real time imaging of breast surgical specimens |
| url | http://hdl.handle.net/1721.1/114749 https://orcid.org/0000-0002-2570-0770 https://orcid.org/0000-0003-4156-6484 https://orcid.org/0000-0003-3425-9486 https://orcid.org/0000-0003-4811-3429 https://orcid.org/0000-0002-0828-4357 |
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