Regulation of Peripheral Myelination through Transcriptional Buffering of Egr2 by an Antisense Long Non-coding RNA
Precise regulation of Egr2 transcription is fundamentally important to the control of peripheral myelination. Here, we describe a long non-coding RNA antisense to the promoter of Egr2 (Egr2-AS-RNA). During peripheral nerve injury, the expression of Egr2-AS-RNA is increased and correlates with decrea...
Main Authors: | Martinez-Moreno, Margot, Zepecki, John P., Olaru, Alexander, Ness, Jennifer K., Tapinos, Nikos, O'Shea, Timothy Mark, Langer, Robert S |
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Other Authors: | Massachusetts Institute of Technology. Institute for Medical Engineering & Science |
Format: | Article |
Published: |
Elsevier
2018
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Online Access: | http://hdl.handle.net/1721.1/114935 https://orcid.org/0000-0003-4255-0492 |
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