Enabling multiplexed testing of pooled donor cells through whole-genome sequencing
We describe a method that enables the multiplex screening of a pool of many different donor cell lines. Our method accurately predicts each donor proportion from the pool without requiring the use of unique DNA barcodes as markers of donor identity. Instead, we take advantage of common single nucleo...
Main Authors: | Chan, Yingleong, Chan, Ying K, Guo, Xiaoge, Chavez, Alejandro, Lim, Elaine T, Church, George M, Chan, Ying Kai, Goodman, Daniel B., Lim, Elaine T., Church, George M., Goodman, Daniel Bryan |
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Other Authors: | Institute for Medical Engineering and Science |
Format: | Article |
Language: | English |
Published: |
BioMed Central Ltd
2018
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Online Access: | http://hdl.handle.net/1721.1/114969 https://orcid.org/0000-0003-3759-6883 |
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