Enabling multiplexed testing of pooled donor cells through whole-genome sequencing

We describe a method that enables the multiplex screening of a pool of many different donor cell lines. Our method accurately predicts each donor proportion from the pool without requiring the use of unique DNA barcodes as markers of donor identity. Instead, we take advantage of common single nucleo...

Full description

Bibliographic Details
Main Authors: Chan, Yingleong, Chan, Ying K, Guo, Xiaoge, Chavez, Alejandro, Lim, Elaine T, Church, George M, Chan, Ying Kai, Goodman, Daniel B., Lim, Elaine T., Church, George M., Goodman, Daniel Bryan
Other Authors: Institute for Medical Engineering and Science
Format: Article
Language:English
Published: BioMed Central Ltd 2018
Online Access:http://hdl.handle.net/1721.1/114969
https://orcid.org/0000-0003-3759-6883

Similar Items