Paper and Fiber-Based Bio-Diagnostic Platforms: Current Challenges and Future Needs
In this perspective article, some of the latest paper and fiber-based bio-analytical platforms are summarized, along with their fabrication strategies, the processing behind the product development, and the embedded systems in which paper or fiber materials were integrated. The article also reviews...
| Main Authors: | , , |
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| Other Authors: | |
| Format: | Article |
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MDPI AG
2018
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| Online Access: | http://hdl.handle.net/1721.1/115085 |
| _version_ | 1811083596340920320 |
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| author | Hosseini, Samira Vázquez-Villegas, Patricia Martínez-Chapa, Sergio O. |
| author2 | Massachusetts Institute of Technology. Research Laboratory of Electronics |
| author_facet | Massachusetts Institute of Technology. Research Laboratory of Electronics Hosseini, Samira Vázquez-Villegas, Patricia Martínez-Chapa, Sergio O. |
| author_sort | Hosseini, Samira |
| collection | MIT |
| description | In this perspective article, some of the latest paper and fiber-based bio-analytical platforms are summarized, along with their fabrication strategies, the processing behind the product development, and the embedded systems in which paper or fiber materials were integrated. The article also reviews bio-recognition applications of paper/fiber-based devices, the detected analytes of interest, applied detection techniques, the related evaluation parameters, the type and duration of the assays, as well as the advantages and disadvantages of each technique. Moreover, some of the existing challenges of utilizing paper and/or fiber materials are discussed. These include control over the physical characteristics (porosity, permeability, wettability) and the chemical properties (surface functionality) of paper/fiber materials are discussed. Other aspects of the review focus on shelf life, the multi-functionality of the platforms, readout strategies, and other challenges that have to be addressed in order to obtain reliable detection outcomes. Keywords: paper-based bio-analytical devices; shelf life; equipment-free bio-recognition; flow rate; readout strategies; multi-functional platforms |
| first_indexed | 2024-09-23T12:35:35Z |
| format | Article |
| id | mit-1721.1/115085 |
| institution | Massachusetts Institute of Technology |
| last_indexed | 2024-09-23T12:35:35Z |
| publishDate | 2018 |
| publisher | MDPI AG |
| record_format | dspace |
| spelling | mit-1721.1/1150852022-09-28T08:53:52Z Paper and Fiber-Based Bio-Diagnostic Platforms: Current Challenges and Future Needs Hosseini, Samira Vázquez-Villegas, Patricia Martínez-Chapa, Sergio O. Massachusetts Institute of Technology. Research Laboratory of Electronics Hosseini, Samira In this perspective article, some of the latest paper and fiber-based bio-analytical platforms are summarized, along with their fabrication strategies, the processing behind the product development, and the embedded systems in which paper or fiber materials were integrated. The article also reviews bio-recognition applications of paper/fiber-based devices, the detected analytes of interest, applied detection techniques, the related evaluation parameters, the type and duration of the assays, as well as the advantages and disadvantages of each technique. Moreover, some of the existing challenges of utilizing paper and/or fiber materials are discussed. These include control over the physical characteristics (porosity, permeability, wettability) and the chemical properties (surface functionality) of paper/fiber materials are discussed. Other aspects of the review focus on shelf life, the multi-functionality of the platforms, readout strategies, and other challenges that have to be addressed in order to obtain reliable detection outcomes. Keywords: paper-based bio-analytical devices; shelf life; equipment-free bio-recognition; flow rate; readout strategies; multi-functional platforms 2018-04-30T14:54:50Z 2018-04-30T14:54:50Z 2017-08 2017-07 2018-04-25T15:17:43Z Article http://purl.org/eprint/type/JournalArticle 2076-3417 http://hdl.handle.net/1721.1/115085 Hosseini, Samira et al. "Paper and Fiber-Based Bio-Diagnostic Platforms: Current Challenges and Future Needs." Applied Sciences 7, 8 (August 2017): 863 © 2017 The Authors http://dx.doi.org/10.3390/app7080863 Applied Sciences Creative Commons Attribution http://creativecommons.org/licenses/by/4.0/ application/pdf MDPI AG Multidisciplinary Digital Publishing Institute |
| spellingShingle | Hosseini, Samira Vázquez-Villegas, Patricia Martínez-Chapa, Sergio O. Paper and Fiber-Based Bio-Diagnostic Platforms: Current Challenges and Future Needs |
| title | Paper and Fiber-Based Bio-Diagnostic Platforms: Current Challenges and Future Needs |
| title_full | Paper and Fiber-Based Bio-Diagnostic Platforms: Current Challenges and Future Needs |
| title_fullStr | Paper and Fiber-Based Bio-Diagnostic Platforms: Current Challenges and Future Needs |
| title_full_unstemmed | Paper and Fiber-Based Bio-Diagnostic Platforms: Current Challenges and Future Needs |
| title_short | Paper and Fiber-Based Bio-Diagnostic Platforms: Current Challenges and Future Needs |
| title_sort | paper and fiber based bio diagnostic platforms current challenges and future needs |
| url | http://hdl.handle.net/1721.1/115085 |
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