Our Evolving Understanding of the Mechanism of Quinolones

Our Evolving Understanding of the Mechanism of Quinolones

The maintenance of DNA supercoiling is essential for the proper regulation of a plethora of biological processes. As a consequence of this mode of regulation, ahead of the replication fork, DNA replication machinery is prone to introducing supercoiled regions into the DNA double helix. Resolution of...

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Bibliographic Details
Main Authors: Gutierrez, Arnaud, Stokes, Jonathan M., Matic, Ivan, Stokes, Jonathan
Other Authors: Massachusetts Institute of Technology. Institute for Medical Engineering & Science
Format: Article
Published: MDPI AG 2018
Online Access:http://hdl.handle.net/1721.1/115086

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