Role of framework mutations and antibody flexibility in the evolution of broadly neutralizing antibodies
Eliciting antibodies that are cross reactive with surface proteins of diverse strains of highly mutable pathogens (e.g., HIV, influenza) could be key for developing effective universal vaccines. Mutations in the framework regions of such broadly neutralizing antibodies (bnAbs) have been reported to...
| Main Authors: | , , , , |
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| Format: | Article |
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eLife Sciences Publications, Ltd
2018
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| Online Access: | http://hdl.handle.net/1721.1/115144 https://orcid.org/0000-0001-9506-5840 https://orcid.org/0000-0003-1467-421X https://orcid.org/0000-0003-1268-9602 |