Human α-Defensin 6: A Small Peptide That Self-Assembles and Protects the Host by Entangling Microbes

Conspectus Human α-defensin 6 (HD6) is a 32-residue cysteine-rich peptide that contributes to innate immunity by protecting the host at mucosal sites. This peptide is produced in small intestinal Paneth cells, stored as an 81-residue precursor peptide named proHD6 in granules, and released into the...

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Bibliographic Details
Main Authors: Chairatana, Phoom, Nolan, Elizabeth Marie
Other Authors: Massachusetts Institute of Technology. Department of Chemistry
Format: Article
Published: American Chemical Society (ACS) 2018
Online Access:http://hdl.handle.net/1721.1/115156
https://orcid.org/0000-0002-5356-3638
https://orcid.org/0000-0002-6153-8803