Favorable outcome of experimental islet xenotransplantation without immunosuppression in a nonhuman primate model of diabetes
Transplantation of pancreatic islets for treating type 1 diabetes is restricted to patients with critical metabolic lability resulting from the need for immunosuppression and the shortage of donor organs. To overcome these barriers, we developed a strategy to macroencap-sulate islets from different...
Main Authors: | Ludwig, Barbara, Ludwig, Stefan, Steffen, Anja, Knauf, Yvonne, Zimerman, Baruch, Heinke, Sophie, Lehmann, Susann, Schubert, Undine, Schmid, Janine, Bleyer, Martina, Schönmann, Uwe, Bonifacio, Ezio, Solimena, Michele, Reichel, Andreas, Schally, Andrew V., Rotem, Avi, Barkai, Uriel, Grinberg-Rashi, Helena, Kaup, Franz-Josef, Avni, Yuval, Jones, Peter, Bornstein, Stefan R., Colton, Clark K |
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Other Authors: | Massachusetts Institute of Technology. Department of Chemical Engineering |
Format: | Article |
Published: |
National Academy of Sciences (U.S.)
2018
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Online Access: | http://hdl.handle.net/1721.1/115205 https://orcid.org/0000-0001-8777-9632 |
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