Experience-dependent synaptic plasticity in V1 occurs without microglial CX3CR1

Brief monocular deprivation (MD) shifts ocular dominance and reduces the density of thalamic synapses in layer 4 of the mouse primary visual cortex (V1). We found that microglial lysosome content is also increased as a result of MD. Previous studies have shown that the microglial fractalkine recepto...

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Bibliographic Details
Main Authors: Maher, Erin E., Welsh, Christina A., Stevens, Beth, Erisir, Alev, Schecter, Rachel Ward, Bear, Mark
Other Authors: Picower Institute for Learning and Memory
Format: Article
Published: Society for Neuroscience 2018
Online Access:http://hdl.handle.net/1721.1/115288
https://orcid.org/0000-0003-1986-4207