Design of a portable, wide field of view, GPU-accelerated multiphoton imaging system for real-time imaging of breast surgical specimens
We present a portable multiphoton system designed for evaluating centimeter-scale surgical margins on surgical breast specimens in a clinical setting. The system is designed to produce large field of view images at a high frame rate, while using GPU processing to render low latency, video-rate virtu...
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SPIE
2018
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| Online Access: | http://hdl.handle.net/1721.1/115408 https://orcid.org/0000-0002-2570-0770 https://orcid.org/0000-0003-4156-6484 https://orcid.org/0000-0003-3425-9486 https://orcid.org/0000-0003-4811-3429 https://orcid.org/0000-0002-0828-4357 |
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| author | Husvogt, Lennart Vardeh, Hilde Sheykin, Yury Faulkner-Jones, Beverly E. Hornegger, Joachim Brooker, Jeff Cable, Alex Connolly, James L. Giacomelli, Michael Yoshitake, Tadayuki Cahill, Lucas Christopher Ahsen, Osman Oguz Fujimoto, James G |
| author2 | Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science |
| author_facet | Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science Husvogt, Lennart Vardeh, Hilde Sheykin, Yury Faulkner-Jones, Beverly E. Hornegger, Joachim Brooker, Jeff Cable, Alex Connolly, James L. Giacomelli, Michael Yoshitake, Tadayuki Cahill, Lucas Christopher Ahsen, Osman Oguz Fujimoto, James G |
| author_sort | Husvogt, Lennart |
| collection | MIT |
| description | We present a portable multiphoton system designed for evaluating centimeter-scale surgical margins on surgical breast specimens in a clinical setting. The system is designed to produce large field of view images at a high frame rate, while using GPU processing to render low latency, video-rate virtual H&E images for real-time assessment. The imaging system and virtual H&E rendering algorithm are demonstrated by imaging unfixed human breast tissue in a clinical setting. Keywords: multiphoton, histology, surgical pathology, H&E |
| first_indexed | 2024-09-23T14:40:16Z |
| format | Article |
| id | mit-1721.1/115408 |
| institution | Massachusetts Institute of Technology |
| last_indexed | 2024-09-23T14:40:16Z |
| publishDate | 2018 |
| publisher | SPIE |
| record_format | dspace |
| spelling | mit-1721.1/1154082022-10-01T21:59:01Z Design of a portable, wide field of view, GPU-accelerated multiphoton imaging system for real-time imaging of breast surgical specimens Husvogt, Lennart Vardeh, Hilde Sheykin, Yury Faulkner-Jones, Beverly E. Hornegger, Joachim Brooker, Jeff Cable, Alex Connolly, James L. Giacomelli, Michael Yoshitake, Tadayuki Cahill, Lucas Christopher Ahsen, Osman Oguz Fujimoto, James G Massachusetts Institute of Technology. Department of Electrical Engineering and Computer Science Massachusetts Institute of Technology. Research Laboratory of Electronics Giacomelli, Michael Yoshitake, Tadayuki Cahill, Lucas Christopher Ahsen, Osman Oguz Fujimoto, James G We present a portable multiphoton system designed for evaluating centimeter-scale surgical margins on surgical breast specimens in a clinical setting. The system is designed to produce large field of view images at a high frame rate, while using GPU processing to render low latency, video-rate virtual H&E images for real-time assessment. The imaging system and virtual H&E rendering algorithm are demonstrated by imaging unfixed human breast tissue in a clinical setting. Keywords: multiphoton, histology, surgical pathology, H&E 2018-05-16T18:12:55Z 2018-05-16T18:12:55Z 2016-03 2016-03 2018-03-30T15:25:12Z Article http://purl.org/eprint/type/ConferencePaper 0277-786X 1996-756X http://hdl.handle.net/1721.1/115408 Giacomelli, Michael G. et al. “Design of a Portable Wide Field of View GPU-Accelerated Multiphoton Imaging System for Real-Time Imaging of Breast Surgical Specimens.” Proceedings Volume 9712, Multiphoton Microscopy in the Biomedical Sciences XVI, 13-18 February, 2016, San Francisco, California, SPIE, 2016. https://orcid.org/0000-0002-2570-0770 https://orcid.org/0000-0003-4156-6484 https://orcid.org/0000-0003-3425-9486 https://orcid.org/0000-0003-4811-3429 https://orcid.org/0000-0002-0828-4357 http://dx.doi.org/10.1117/12.2209241 Proceedings Volume 9712, Multiphoton Microscopy in the Biomedical Sciences XVI Article is made available in accordance with the publisher's policy and may be subject to US copyright law. Please refer to the publisher's site for terms of use. application/pdf SPIE SPIE |
| spellingShingle | Husvogt, Lennart Vardeh, Hilde Sheykin, Yury Faulkner-Jones, Beverly E. Hornegger, Joachim Brooker, Jeff Cable, Alex Connolly, James L. Giacomelli, Michael Yoshitake, Tadayuki Cahill, Lucas Christopher Ahsen, Osman Oguz Fujimoto, James G Design of a portable, wide field of view, GPU-accelerated multiphoton imaging system for real-time imaging of breast surgical specimens |
| title | Design of a portable, wide field of view, GPU-accelerated multiphoton imaging system for real-time imaging of breast surgical specimens |
| title_full | Design of a portable, wide field of view, GPU-accelerated multiphoton imaging system for real-time imaging of breast surgical specimens |
| title_fullStr | Design of a portable, wide field of view, GPU-accelerated multiphoton imaging system for real-time imaging of breast surgical specimens |
| title_full_unstemmed | Design of a portable, wide field of view, GPU-accelerated multiphoton imaging system for real-time imaging of breast surgical specimens |
| title_short | Design of a portable, wide field of view, GPU-accelerated multiphoton imaging system for real-time imaging of breast surgical specimens |
| title_sort | design of a portable wide field of view gpu accelerated multiphoton imaging system for real time imaging of breast surgical specimens |
| url | http://hdl.handle.net/1721.1/115408 https://orcid.org/0000-0002-2570-0770 https://orcid.org/0000-0003-4156-6484 https://orcid.org/0000-0003-3425-9486 https://orcid.org/0000-0003-4811-3429 https://orcid.org/0000-0002-0828-4357 |
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