Bispecific antibody generated with sortase and click chemistry has broad antiinfluenza virus activity
Bispecific antibodies have therapeutic potential by expanding the functions of conventional antibodies. Many different formats of bispecific antibodies have meanwhile been developed. Most are genetic modifications of the antibody backbone to facilitate incorporation of two different variable domains...
Main Authors: | Wagner, Koen, Kwakkenbos, Mark J., Claassen, Yvonne B., Maijoor, Kelly, Böhne, Martino, van der Sluijs, Koenraad F., Witte, Martin D., van Zoelen, Diana J., Cornelissen, Lisette A., Beaumont, Tim, Bakker, Arjen Q., Spits, Hergen, Ploegh, Hidde |
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Other Authors: | Massachusetts Institute of Technology. Department of Biology |
Format: | Article |
Published: |
National Academy of Sciences (U.S.)
2018
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Online Access: | http://hdl.handle.net/1721.1/115434 https://orcid.org/0000-0002-1090-6071 |
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