Bispecific antibody generated with sortase and click chemistry has broad antiinfluenza virus activity

Bispecific antibodies have therapeutic potential by expanding the functions of conventional antibodies. Many different formats of bispecific antibodies have meanwhile been developed. Most are genetic modifications of the antibody backbone to facilitate incorporation of two different variable domains...

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Bibliographic Details
Main Authors: Wagner, Koen, Kwakkenbos, Mark J., Claassen, Yvonne B., Maijoor, Kelly, Böhne, Martino, van der Sluijs, Koenraad F., Witte, Martin D., van Zoelen, Diana J., Cornelissen, Lisette A., Beaumont, Tim, Bakker, Arjen Q., Spits, Hergen, Ploegh, Hidde
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Published: National Academy of Sciences (U.S.) 2018
Online Access:http://hdl.handle.net/1721.1/115434
https://orcid.org/0000-0002-1090-6071

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