Human osteochondritis dissecans fragment-derived chondrocyte characteristics ex vivo, after monolayer expansion-induced de-differentiation, and after re-differentiation in alginate bead culture

Human osteochondritis dissecans fragment-derived chondrocyte characteristics ex vivo, after monolayer expansion-induced de-differentiation, and after re-differentiation in alginate bead culture

Background Autologous chondrocyte implantation (ACI) is a therapy for articular cartilage and osteochondral lesions that relies on notch- or trochlea-derived primary chondrocytes. An alternative cell source for ACI could be osteochondritis dissecans (OCD) fragment-derived chondrocyt...

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Bibliographic Details
Main Authors: Aurich, Matthias, Gras, Florian, Hofmann, Gunther O., Rolauffs, Bernd G
Other Authors: Massachusetts Institute of Technology. Center for Biomedical Engineering
Format: Article
Language:English
Published: BioMed Central 2018
Online Access:http://hdl.handle.net/1721.1/115986

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