MicroRNA-126-mediated control of cell fate in B-cell myeloid progenitors as a potential alternative to transcriptional factors

MicroRNA-126-mediated control of cell fate in B-cell myeloid progenitors as a potential alternative to transcriptional factors

Lineage specification is thought to be largely regulated at the level of transcription, where lineage-specific transcription factors drive specific cell fates. MicroRNAs (miR), vital to many cell functions, act posttranscriptionally to decrease the expression of target mRNAs. MLL-AF4 acute lymphocyt...

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Bibliographic Details
Main Authors: Okuyama, K., Ikawa, T., Gentner, B., Hozumi, K., Harnprasopwat, R., Lu, J., Yamashita, R., Ha, D., Toyoshima, T., Chanda, B., Kawamata, T., Yokoyama, K., Wang, S., Ando, K., Lodish, H. F., Tojo, A., Kawamoto, H., Kotani, A., Lodish, Harvey F
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Published: National Academy of Sciences (U.S.) 2018
Online Access:http://hdl.handle.net/1721.1/116191
https://orcid.org/0000-0002-7029-7415

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