Sequence, Structure, and Context Preferences of Human RNA Binding Proteins
RNA binding proteins (RBPs) orchestrate the production, processing, and function of mRNAs. Here, we present the affinity landscapes of 78 human RBPs using an unbiased assay that determines the sequence, structure, and context preferences of these proteins in vitro by deep sequencing of bound RNAs. T...
Main Authors: | Freese, Peter, Alexis, Maria S., Van Nostrand, Eric L., Pratt, Gabriel A., Yeo, Gene W., Graveley, Brenton R., Dominguez, Daniel, Su, Amanda J, Hochman, Myles, Palden, Tsultrim, Bazile, Cassandra, Lambert, Nicole, Burge, Christopher B |
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Other Authors: | Massachusetts Institute of Technology. Department of Biological Engineering |
Format: | Article |
Published: |
Elsevier
2018
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Online Access: | http://hdl.handle.net/1721.1/116339 https://orcid.org/0000-0002-6936-6399 |
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