7-Carboxy-7-deazaguanine Synthase: A Radical

7-Carboxy-7-deazaguanine Synthase: A Radical

Radical S-adenosyl-L-methionine (SAM) enzymes are widely distributed and catalyze diverse reactions. SAM binds to the unique iron atom of a site-differentiated [4Fe-4S] cluster and is reductively cleaved to generate a 5'-deoxyadenosyl radical, which initiates turnover. 7-Carboxy-7-deazaguanine...

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Bibliographic Details
Main Authors: Bruender, Nathan A., McCarty, Reid M., Bandarian, Vahe, Grell, Tsehai Ariane, Dowling, Daniel P., Drennan, Catherine L
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Published: American Chemical Society (ACS) 2018
Online Access:http://hdl.handle.net/1721.1/116404
https://orcid.org/0000-0001-8578-7559
https://orcid.org/0000-0001-5486-2755

Internet

http://hdl.handle.net/1721.1/116404
https://orcid.org/0000-0001-8578-7559
https://orcid.org/0000-0001-5486-2755

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