Targeting Bacillosamine Biosynthesis in Bacterial Pathogens: Development of Inhibitors to a Bacterial Amino-Sugar Acetyltransferase from Campylobacter Jejuni
The glycoproteins of selected microbial pathogens often include highly modified carbohydrates such as 2,4-diacetamidobacillosamine (diNAcBac). These glycoconjugates are involved in host-cell interactions and may be associated with the virulence of medically significant Gram-negative bacteria. In lig...
Main Authors: | Ciulli, Alessio, De Schutter, Joris, Morrison, James P., Morrison, Michael James, Imperiali, Barbara |
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Other Authors: | Massachusetts Institute of Technology. Department of Biology |
Format: | Article |
Published: |
American Chemical Society (ACS)
2018
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Online Access: | http://hdl.handle.net/1721.1/116523 https://orcid.org/0000-0003-4442-1491 https://orcid.org/0000-0002-5749-7869 |
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