Targeting Bacillosamine Biosynthesis in Bacterial Pathogens: Development of Inhibitors to a Bacterial Amino-Sugar Acetyltransferase from Campylobacter Jejuni

The glycoproteins of selected microbial pathogens often include highly modified carbohydrates such as 2,4-diacetamidobacillosamine (diNAcBac). These glycoconjugates are involved in host-cell interactions and may be associated with the virulence of medically significant Gram-negative bacteria. In lig...

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Bibliographic Details
Main Authors: Ciulli, Alessio, De Schutter, Joris, Morrison, James P., Morrison, Michael James, Imperiali, Barbara
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Published: American Chemical Society (ACS) 2018
Online Access:http://hdl.handle.net/1721.1/116523
https://orcid.org/0000-0003-4442-1491
https://orcid.org/0000-0002-5749-7869

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