The endoplasmic reticulum may be an Achilles' heel of cancer cells that have undergone an epithelial-to-mesenchymal transition

In a recent report published in Cancer Discovery we identified a novel vulnerability of cancer cells that have undergone an epithelial–mesenchymal transition (EMT) and established that the PERK branch of the unfolded protein response is constitutively activated upon EMT. In this commentary, we summa...

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書目詳細資料
Main Authors: Feng, Yu-xiong, Sokol, Ethan Samuel, Gupta, Piyush
其他作者: Massachusetts Institute of Technology. Department of Biology
格式: Article
出版: Informa UK Limited 2018
在線閱讀:http://hdl.handle.net/1721.1/116526
https://orcid.org/0000-0002-2988-0537
https://orcid.org/0000-0002-9703-1780